DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

The invention of the in vitro selection technique, or SELEX (Systematic Evolution of Ligands
by EXponential enrichment), in the early 1990s, identified single-stranded (ss) nucleic acid …

DNA nanotechnology has significantly progressed in the last four decades, creating nucleic
acid structures widely used in various biological applications. The structural flexibility …

Exosomes have emerged as a promising noninvasive biomarker for early cancer diagnosis
due to their ability to carry specific bioinformation related to cancer cells. However, accurate …

Aptamers are single-stranded DNA or RNA sequences with a unique three-dimensional
structure that allows them to recognize a particular target with high affinity. Although their …

The intersection of microfluidics and aptamer technologies holds particular promise for rapid
progress in a plethora of applications across biomedical science and other areas. Here, the …

While engineered DNA nanoframeworks have been extensively exploited for delivery of
diagnostic and therapeutic regents, DNA tiling-based DNA frameworks amenable to …

Nucleic acid aptamers (Apt) are RNA or DNA fragments that can bind specifically to a target
molecule or to a target substrate with great affinity, thus has attracted great attention for …