Obesity-related heart failure with a preserved ejection fraction: the mechanistic rationale for combining inhibitors of aldosterone, neprilysin, and sodium-glucose …

M Packer, DW Kitzman - JACC: Heart Failure, 2018 - jacc.org
Obesity-related heart failure with a preserved ejection fraction (HFpEF) is an important
phenotype prevalent in the community, especially in people with metabolic disorders (eg …

Capillary rarefaction as an index for the microvascular assessment of hypertensive patients

A Triantafyllou, P Anyfanti, A Pyrpasopoulou… - Current hypertension …, 2015 - Springer
Arterial hypertension represents a leading cause of cardiovascular mortality and morbidity
worldwide through its detrimental effects on target organs. Therefore, the early identification …

Systemic hypertension associated retinal microvascular changes can be detected with optical coherence tomography angiography

C Sun, C Ladores, J Hong, DQ Nguyen, J Chua… - Scientific reports, 2020 - nature.com
A major complication of hypertension is microvascular damage and capillary rarefaction is a
known complication of hypertensive end-organ damage which confers a higher risk of …

Skin microvascular function, as assessed with laser speckle contrast imaging, is impaired in untreated essential and masked hypertension

A Lazaridis, A Triantafyllou, K Dipla, P Dolgyras… - Hypertension …, 2022 - nature.com
Skin microcirculation has been proposed as a model of generalized microvascular function.
Laser speckle contrast imaging (LSCI) is a novel, noninvasive method to assess skin …

Impaired muscle oxygenation and elevated exercise blood pressure in hypertensive patients: links with vascular stiffness

K Dipla, A Triantafyllou, N Koletsos… - …, 2017 - Am Heart Assoc
This study examined in vivo (1) skeletal muscle oxygenation and microvascular function, at
rest and during handgrip exercise, and (2) their association with macrovascular function and …

The importance of microvascular inflammation in ageing and age-related diseases: a position paper from the ESH working group on small arteries, section of …

A Mengozzi, C de Ciuceis, R Dell'oro… - Journal of …, 2023 - journals.lww.com
Microcirculation is pervasive and orchestrates a profound regulatory cross-talk with the
surrounding tissue and organs. Similarly, it is one of the earliest biological systems targeted …

Blunted microvascular reactivity in psoriasis patients in the absence of cardiovascular disease, as assessed by laser speckle contrast imaging

A Margouta, P Anyfanti, A Lazaridis, B Nikolaidou… - Life, 2022 - mdpi.com
Psoriasis is associated with accelerated rates of cardiovascular disease (CVD). Laser
Speckle Contrast Imaging (LSCI) is a novel, non-interventional technique for the dynamic …

Capillary rarefaction associates with albuminuria: the Maastricht Study

RJH Martens, RMA Henry, AJHM Houben… - Journal of the …, 2016 - journals.lww.com
Albuminuria may be a biomarker of generalized (ie, microvascular and macrovascular)
endothelial dysfunction. According to this concept, endothelial dysfunction of the renal …

Skin microvascular dysfunction in systemic lupus erythematosus patients with and without cardiovascular risk factors

N Koletsos, E Gkaliagkousi, A Lazaridis… - …, 2021 - academic.oup.com
Objectives Patients with SLE have increased cardiovascular mortality. Alterations in both
macro-and micro-circulation have been associated with cardiovascular disease. We sought …

Clinical Significance of Altered Vascular Morphology and Function in Normotension

A Triantafyllou, P Anyfanti, N Koletsos… - Current Hypertension …, 2023 - Springer
Abstract Purpose of Review To review current literature examining the presence of
subclinical micro-and macrovascular alterations in normotensive individuals and their …