An important goal in animal breeding is to improve longitudinal traits; that is, traits recorded
multiple times during an individual's lifetime or physiological cycle. Longitudinal traits were …

Organisms usually cope with change in the environment by altering the dynamic trajectory of
gene expression to adjust the complement of active proteins. The identification of particular …

Background This study focused on the dynamics of genome-wide effects on five milk
production and eight fertility traits as well as genetic correlations between the traits. For …

Estimation of the covariance structure of longitudinal processes is a fundamental
prerequisite for the practical deployment of functional map** designed to study the genetic …

Many phenomena of fundamental importance to biology and biomedicine arise as a
dynamic curve, such as organ growth and HIV dynamics. The genetic map** of these traits …

Abstract Key message qFT7. 1, a major QTL for flowering time in Brassica rapa was fine-
mapped to chromosome A07 in a 56.4-kb interval, in which the most likely candidate gene is …

In this study, changes in gene effects for milk production traits were analysed over time.
Such changes can be expected by investigating daily milk production yields, which increase …

Abstract Knowledge of genes influencing longitudinal patterns may offer information about
predicting disease progression. We developed a systematic procedure for testing …

Background Functional map** is a powerful approach for map** quantitative trait loci
(QTLs) that control biological processes. Functional map** incorporates mathematical …

A hierarchical random regression model (Hi-RRM) was extended into a genome-wide
association analysis for longitudinal data, which significantly reduced the dimensionality of …