Signaling pathways and intervention therapies in sepsis

Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Haemodialysis membranes

C Ronco, WR Clark - Nature Reviews Nephrology, 2018 - nature.com
Haemodialysis is an extracorporeal process in which the blood is cleansed via removal of
uraemic retention products by a semipermeable membrane. Traditionally, dialysis …

[HTML][HTML] Extracorporeal blood purification therapies for sepsis

C Monard, T Rimmele, C Ronco - Blood purification, 2019 - karger.com
Extracorporeal blood purification is proposed as an adjuvant therapy for sepsis, aiming at
controlling the associated dysregulation of the immune system, which is known to induce …

Extracorporeal techniques for the treatment of critically ill patients with sepsis beyond conventional blood purification therapy: the promises and the pitfalls

G Ankawi, M Neri, J Zhang, A Breglia, Z Ricci, C Ronco - Critical care, 2018 - Springer
Sepsis is one of the leading causes of morbidity and mortality worldwide. It is characterized
by a dysregulated immune response to infections that results in life-threatening organ …

[HTML][HTML] Renal replacement techniques in septic shock

T Hellman, P Uusalo, MJ Järvisalo - International Journal of Molecular …, 2021 - mdpi.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection; it carries a risk for mortality, considerably exceeding that of a mere …

Blood purification techniques for sepsis and septic AKI

T Girardot, A Schneider, T Rimmele - Seminars in nephrology, 2019 - Elsevier
Sepsis is the primary cause of acute kidney injury in critically ill patients. During the past
decades, several extracorporeal blood purification techniques have been developed for …

CRRT for sepsis-induced acute kidney injury

S Romagnoli, Z Ricci, C Ronco - Current opinion in critical care, 2018 - journals.lww.com
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Advances in the development of biomaterials for endotoxin adsorption in sepsis

Q Yang, Y Li, P Tuohuti, Z Qin, Z Zhang… - … in Bioengineering and …, 2021 - frontiersin.org
Sepsis, a life-threatening and intractable disease without any specific treatment, is activated
by endotoxin. Some attempts at removing endotoxin to treat sepsis from the blood circulation …

Organ dysfunction during continuous veno-venous high cut-off hemodialysis in patients with septic acute kidney injury: a prospective observational study

G Villa, C Chelazzi, E Morettini, L Zamidei, S Valente… - PLoS …, 2017 - journals.plos.org
Background Continuous veno-venous hemodialysis with high cut-off membranes (HCO-
CVVHD) removes inflammatory mediators involved in organ dysfunction during sepsis. The …