Mechanics and functional consequences of nuclear deformations
As the home of cellular genetic information, the nucleus has a critical role in determining cell
fate and function in response to various signals and stimuli. In addition to biochemical …
fate and function in response to various signals and stimuli. In addition to biochemical …
[HTML][HTML] Intermediate, but not average: The unusual lives of the nuclear lamin proteins
A Buchwalter - Current Opinion in Cell Biology, 2023 - Elsevier
The nuclear lamins are polymeric intermediate filament proteins that scaffold the nucleus
and organize the genome in nearly all eukaryotic cells. This review focuses on the dynamic …
and organize the genome in nearly all eukaryotic cells. This review focuses on the dynamic …
The laminin–keratin link shields the nucleus from mechanical deformation and signalling
The mechanical properties of the extracellular matrix dictate tissue behaviour. In epithelial
tissues, laminin is a very abundant extracellular matrix component and a key supporting …
tissues, laminin is a very abundant extracellular matrix component and a key supporting …
Effects of forces on chromatin
Chromatin is a unique structure of DNA and histone proteins in the cell nucleus and the site
of dynamic regulation of gene expression. Soluble factors are known to affect the chromatin …
of dynamic regulation of gene expression. Soluble factors are known to affect the chromatin …
Fabrication of polycaprolactone electrospun fibres with retinyl acetate for antioxidant delivery in a ROS-mimicking environment
Background: Increased cancer rates denote that one in two people will be diagnosed with
cancer in their lifetime. Over 60% of cancer patients receive radiotherapy, either as a stand …
cancer in their lifetime. Over 60% of cancer patients receive radiotherapy, either as a stand …
3D micropattern force triggers YAP nuclear entry by transport across nuclear pores and modulates stem cells paracrine
Y Li, Z Zhong, C Xu, X Wu, J Li, W Tao… - National Science …, 2023 - academic.oup.com
Biophysical cues of the cellular microenvironment tremendously influence cell behavior by
mechanotransduction. However, it is still unclear how cells sense and transduce the …
mechanotransduction. However, it is still unclear how cells sense and transduce the …
LMNA Reduced Acquired Resistance to Erlotinib in NSCLC by Reversing the Epithelial–Mesenchymal Transition via the FGFR/MAPK/c-fos Signaling Pathway
C Hu, A Zhou, X Hu, Y ** zebrafish retina
M Maia-Gil, M Gorjão, R Belousov, JA Espina, J Coelho… - Current Biology, 2024 - cell.com
Nuclear positioning is a crucial aspect of cell and developmental biology. One example is
the apical movement of nuclei in neuroepithelia before mitosis, which is essential for proper …
the apical movement of nuclei in neuroepithelia before mitosis, which is essential for proper …
A Cyclical Magneto‐Responsive Massage Dressing for Wound Healing
M Zhu, Z Hu, N Liu, K Yao, G Hong, Y Li, Y Chen, H He… - Small, 2024 - Wiley Online Library
Tissue development is mediated by a combination of mechanical and biological signals.
Currently, there are many reports on biological signals regulating repair. However …
Currently, there are many reports on biological signals regulating repair. However …