Glucose metabolism in normal aging and Alzheimer's disease: methodological and physiological considerations for PET studies

L Mosconi - Clinical and translational imaging, 2013 - Springer
Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder associated with
progressive loss of cognitive function. 2-[18 F] fluoro-2-deoxy-d-glucose (FDG) positron …

Cortical hypometabolism and hypoperfusion in Parkinson's disease is extensive: probably even at early disease stages

P Borghammer, M Chakravarty, KY Jonsdottir… - Brain Structure and …, 2010 - Springer
Recent cerebral blood flow (CBF) and glucose consumption (CMRglc) studies of Parkinson's
disease (PD) revealed conflicting results. Using simulated data, we previously demonstrated …

Association of insulin resistance with cerebral glucose uptake in late middle–aged adults at risk for Alzheimer disease

AA Willette, BB Bendlin, EJ Starks, AC Birdsill… - JAMA …, 2015 - jamanetwork.com
Importance Converging evidence suggests that Alzheimer disease (AD) involves insulin
signaling impairment. Patients with AD and individuals at risk for AD show reduced glucose …

[KNIHA][B] Decision forests for computer vision and medical image analysis

A Criminisi, J Shotton - 2013 - books.google.com
Decision forests (also known as random forests) are an indispensable tool for automatic
image analysis. This practical and easy-to-follow text explores the theoretical underpinnings …

Random forest-based similarity measures for multi-modal classification of Alzheimer's disease

KR Gray, P Aljabar, RA Heckemann, A Hammers… - NeuroImage, 2013 - Elsevier
Neurodegenerative disorders, such as Alzheimer's disease, are associated with changes in
multiple neuroimaging and biological measures. These may provide complementary …

Multi-modal classification of Alzheimer's disease using nonlinear graph fusion

T Tong, K Gray, Q Gao, L Chen, D Rueckert… - Pattern recognition, 2017 - Elsevier
Accurate diagnosis of Alzheimer's disease (AD) and its prodromal stage mild cognitive
impairment (MCI) is of great interest to patients and clinicians. Recent studies have …

A Standardized [18F]-FDG-PET Template for Spatial Normalization in Statistical Parametric Map** of Dementia

PA Della Rosa, C Cerami, F Gallivanone, A Prestia… - Neuroinformatics, 2014 - Springer
Abstract [18 F]-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) is a widely
used diagnostic tool that can detect and quantify pathophysiology, as assessed through …

[HTML][HTML] Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting

D Perani, PA Della Rosa, C Cerami, F Gallivanone… - NeuroImage: Clinical, 2014 - Elsevier
Diagnostic accuracy in FDG-PET imaging highly depends on the operating procedures. In
this clinical study on dementia, we compared the diagnostic accuracy at a single-subject …

The default mode network and cognition in Parkinson's disease: A multimodal resting‐state network approach

MC Ruppert, A Greuel, J Freigang… - Human brain …, 2021 - Wiley Online Library
Involvement of the default mode network (DMN) in cognitive symptoms of Parkinson's
disease (PD) has been reported by resting‐state functional MRI (rsfMRI) studies. However …

Typical cerebral metabolic patterns in neurodegenerative brain diseases

LK Teune, AL Bartels, BM de Jong… - Movement …, 2010 - Wiley Online Library
The differential diagnosis of neurodegenerative brain diseases on clinical grounds is
difficult, especially at an early disease stage. Several studies have found specific regional …