[HTML][HTML] Call to action to properly utilize electron microscopy to measure organelles to monitor disease
This review provides an overview of the current methods for quantifying mitochondrial
ultrastructure, including cristae morphology, mitochondrial contact sites, and recycling …
ultrastructure, including cristae morphology, mitochondrial contact sites, and recycling …
Mitochondria in disease: changes in shapes and dynamics
Mitochondrial structure often determines the function of these highly dynamic,
multifunctional, eukaryotic organelles, which are essential for maintaining cellular health …
multifunctional, eukaryotic organelles, which are essential for maintaining cellular health …
3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex
During aging, muscle gradually undergoes sarcopenia, the loss of function associated with
loss of mass, strength, endurance, and oxidative capacity. However, the 3D structural …
loss of mass, strength, endurance, and oxidative capacity. However, the 3D structural …
Defining mitochondrial cristae morphology changes induced by aging in brown adipose tissue
Mitochondria are required for energy production and even give brown adipose tissue (BAT)
its characteristic color due to their high iron content and abundance. The physiological …
its characteristic color due to their high iron content and abundance. The physiological …
Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging
With sparse treatment options, cardiac disease remains a significant cause of death among
humans. As a person ages, mitochondria breakdown and the heart becomes less efficient …
humans. As a person ages, mitochondria breakdown and the heart becomes less efficient …
Current trends in luminescence-based assessment of apoptosis
Apoptosis, the most extensively studied type of cell death, is known to play a crucial role in
numerous processes such as elimination of unwanted cells or cellular debris, growth, control …
numerous processes such as elimination of unwanted cells or cellular debris, growth, control …
Connection Between HIV and Mitochondria in Cardiovascular Disease and Implications for Treatments
HIV infection and antiretroviral therapy alter mitochondrial function, which can progressively
lead to mitochondrial damage and accelerated aging. The interaction between persistent …
lead to mitochondrial damage and accelerated aging. The interaction between persistent …
A workshop on mitochondria for students to improve understanding of science and hypothesis forming
There remains a clear deficiency in recruiting middle school students in science, technology,
engineering, mathematics, and medicine fields, especially for those students entering …
engineering, mathematics, and medicine fields, especially for those students entering …
Quantitative assessment of morphological changes in lipid droplets and lipid–mito interactions with aging in brown adipose
The physical characteristics of brown adipose tissue (BAT) are defined by the presence of
multilocular lipid droplets (LDs) within the brown adipocytes and a high abundance of iron …
multilocular lipid droplets (LDs) within the brown adipocytes and a high abundance of iron …
ATF4‐dependent increase in mitochondrial‐endoplasmic reticulum tethering following OPA1 deletion in skeletal muscle
Mitochondria and endoplasmic reticulum (ER) contact sites (MERCs) are protein‐and lipid‐
enriched hubs that mediate interorganellar communication by contributing to the dynamic …
enriched hubs that mediate interorganellar communication by contributing to the dynamic …