Synaptic specificity, recognition molecules, and assembly of neural circuits
JR Sanes, SL Zipursky - Cell, 2020 - cell.com
Develo** neurons connect in specific and stereotyped ways to form the complex circuits
that underlie brain function. By comparison to earlier steps in neural development, progress …
that underlie brain function. By comparison to earlier steps in neural development, progress …
Adhesion protein structure, molecular affinities, and principles of cell-cell recognition
The ability of cells to organize into multicellular structures in precise patterns requires that
they" recognize" one another with high specificity. We discuss recent progress in …
they" recognize" one another with high specificity. We discuss recent progress in …
Molecular logic of synaptic diversity between Drosophila tonic and phasic motoneurons
Although neuronal subtypes display unique synaptic organization and function, the
underlying transcriptional differences that establish these features are poorly understood. To …
underlying transcriptional differences that establish these features are poorly understood. To …
Physiologic and nanoscale distinctions define glutamatergic synapses in tonic vs phasic neurons
Neurons exhibit a striking degree of functional diversity, each one tuned to the needs of the
circuitry in which it is embedded. A fundamental functional dichotomy occurs in activity …
circuitry in which it is embedded. A fundamental functional dichotomy occurs in activity …
Coordination between stochastic and deterministic specification in the Drosophila visual system
M Courgeon, C Desplan - Science, 2019 - science.org
INTRODUCTION Neuronal fate decisions must be coordinated across brain regions so that
the proper stoichiometry of distinct afferents and their target neurons is established. Many …
the proper stoichiometry of distinct afferents and their target neurons is established. Many …
Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in Drosophila color vision circuits
KP Menon, V Kulkarni, S Takemura, M Anaya, K Zinn - Elife, 2019 - elifesciences.org
Drosophila R7 UV photoreceptors (PRs) are divided into yellow (y) and pale (p) subtypes.
yR7 PRs express the Dpr11 cell surface protein and are presynaptic to Dm8 amacrine …
yR7 PRs express the Dpr11 cell surface protein and are presynaptic to Dm8 amacrine …
Structural and functional synaptic plasticity induced by convergent synapse loss in the Drosophila neuromuscular circuit
Y Wang, M Lobb-Rabe, J Ashley, V Anand… - Journal of …, 2021 - Soc Neuroscience
Throughout the nervous system, the convergence of two or more presynaptic inputs on a
target cell is commonly observed. The question we ask here is to what extent converging …
target cell is commonly observed. The question we ask here is to what extent converging …
Control of synaptic specificity by establishing a relative preference for synaptic partners
The ability of neurons to identify correct synaptic partners is fundamental to the proper
assembly and function of neural circuits. Relative to other steps in circuit formation such as …
assembly and function of neural circuits. Relative to other steps in circuit formation such as …
Structure and evolution of neuronal wiring receptors and ligands
One of the fundamental properties of a neuronal circuit is the map of its connections. The
cellular and developmental processes that allow for the growth of axons and dendrites …
cellular and developmental processes that allow for the growth of axons and dendrites …
Synaptic properties and plasticity mechanisms of invertebrate tonic and phasic neurons
NA Aponte-Santiago, JT Littleton - Frontiers in Physiology, 2020 - frontiersin.org
Defining neuronal cell types and their associated biophysical and synaptic diversity has
become an important goal in neuroscience as a mechanism to create comprehensive brain …
become an important goal in neuroscience as a mechanism to create comprehensive brain …