The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …

Background Limited data are available for the efficacy of triple therapy with two long-acting
bronchodilators and an inhaled corticosteroid in chronic obstructive pulmonary disease …

Background Previous studies have highlighted a relationship between reduction in rate of
exacerbations with therapies containing inhaled corticosteroids (ICS) and baseline blood …

The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Background Eosinophilic airway inflammation in patients with chronic obstructive pulmonary
disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting …

The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many
diagnostic, prognostic, treatment and management challenges, as the pathogenesis of …

Eosinophils are innate immune cells that, under certain conditions, can be recruited to the
lungs, where they have an incompletely understood role in health and disease. Eosinophils …

COPD is a significant cause of morbidity and mortality. In some patients with COPD,
eosinophils contribute to inflammation that promotes airway obstruction; approximately a …

Inhaled corticosteroids (ICS) combined with bronchodilators can reduce the frequency of
exacerbations in some patients with chronic obstructive pulmonary disease (COPD). There …