Molecular mechanism and physiological functions of clathrin-mediated endocytosis
HT McMahon, E Boucrot - Nature reviews Molecular cell biology, 2011 - nature.com
Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …
Sensory processing at ribbon synapses in the retina and the cochlea
In recent years, sensory neuroscientists have made major efforts to dissect the structure and
function of ribbon synapses which process sensory information in the eye and ear. This …
function of ribbon synapses which process sensory information in the eye and ear. This …
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
T Söllner, MK Bennett, SW Whiteheart, RH Scheller… - Cell, 1993 - cell.com
The SNARE hypothesis holds that a transport vesicle chooses its target for fusion when a
soluble NSF attachment protein (SNAP) receptor on the vesicle (V-SNARE) pairs with its …
soluble NSF attachment protein (SNAP) receptor on the vesicle (V-SNARE) pairs with its …
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse
M Geppert, Y Goda, RE Hammer, C Li, TW Rosahl… - Cell, 1994 - cell.com
Mice carrying a mutation in the synaptotagmin I gene were generated by homologous
recombination. Mutant mice are phenotypically normal as heterozygotes, but die within 48 …
recombination. Mutant mice are phenotypically normal as heterozygotes, but die within 48 …
Caged compounds: photorelease technology for control of cellular chemistry and physiology
GCR Ellis-Davies - Nature methods, 2007 - nature.com
Caged compounds are light-sensitive probes that functionally encapsulate biomolecules in
an inactive form. Irradiation liberates the trapped molecule, permitting targeted perturbation …
an inactive form. Irradiation liberates the trapped molecule, permitting targeted perturbation …
Mechanisms of intracellular protein transport
JE Rothman - Nature, 1994 - nature.com
Recent advances have uncovered the general protein apparatus used by all eukaryotes for
intracellular transport, including secretion and endocytosis, and for triggered exocytosis of …
intracellular transport, including secretion and endocytosis, and for triggered exocytosis of …
Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release
E Neher - Neuron, 1998 - cell.com
Synapse,” intended to contrast our grasp of presynaptic Angleson and Betz (1997) quite
recently reviewed in physiology with our understanding of postsynaptic detail techniques for …
recently reviewed in physiology with our understanding of postsynaptic detail techniques for …
Secretory granule exocytosis
Regulated exocytosis of secretory granules or dense-core granules has been examined in
many well-characterized cell types including neurons, neuroendocrine, endocrine, exocrine …
many well-characterized cell types including neurons, neuroendocrine, endocrine, exocrine …
Lysosomes Behave as Ca2+-regulated Exocytic Vesicles in Fibroblasts and Epithelial Cells
Lysosomes are considered to be a terminal degradative compartment of the endocytic
pathway, into which transport is mostly unidirectional. However, specialized secretory …
pathway, into which transport is mostly unidirectional. However, specialized secretory …
Selective Induction of LTP and LTD by Postsynaptic [Ca2+]i Elevation
SN Yang, YG Tang, RS Zucker - Journal of …, 1999 - journals.physiology.org
Selective Induction of LTP and LTD by Postsynaptic [Ca2+] i Elevation. Long-term
potentiation (LTP) and long-term depression (LTD), two prominent forms of synaptic …
potentiation (LTP) and long-term depression (LTD), two prominent forms of synaptic …