Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

The global spread of antibiotic resistance genes (ARGs) has wreaked havoc with the
treatment efficiency of antibiotics and, ultimately, anti-microbial chemotherapy, and has been …

The formation of biomolecular condensates mediated by a coupling of associative and
segregative phase transitions plays a critical role in controlling diverse cellular functions in …

Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is
generally associated with drug target modification, enzymatic inactivation, and/or transport …

A global medical crisis is unfolding as antibiotics lose effectiveness against a growing
number of bacterial pathogens. Horizontal gene transfer (HGT) contributes significantly to …

Horizontal gene transfer is an important evolutionary force, facilitating bacterial diversity. It is
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …

Bacterial conjugation, also referred to as bacterial sex, is a major horizontal gene transfer
mechanism through which DNA is transferred from a donor to a recipient bacterium by direct …

It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …

Antimicrobial resistance (AMR) poses a worldwide threat to human health and biosecurity.
The spread of antibiotic resistance genes (ARGs) via conjugative plasmid transfer is a major …