Preexposure prophylaxis for the prevention of HIV infection: evidence report and systematic review for the US Preventive Services Task Force

R Chou, C Evans, A Hoverman, C Sun, T Dana… - Jama, 2019 - jamanetwork.com
Importance Effective prevention strategies for HIV infection are an important public health
priority. Preexposure prophylaxis (PrEP) involves use of antiretroviral therapy (ART) daily or …

A systematic review of adherence to oral pre-exposure prophylaxis for HIV–how can we improve uptake and adherence?

D Sidebottom, AM Ekström, S Strömdahl - BMC infectious diseases, 2018 - Springer
Introduction Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk
of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure …

The influence of HIV‐related stigma on PrEP disclosure and adherence among adolescent girls and young women in HPTN 082: a qualitative study

J Velloza, N Khoza, F Scorgie… - Journal of the …, 2020 - Wiley Online Library
Introduction Stigma and disclosure concerns have been key barriers to oral pre‐exposure
prophylaxis (PrEP) adherence for African adolescent girls and young women (AGYW) in …

HIV protective efficacy and correlates of tenofovir blood concentrations in a clinical trial of PrEP for HIV prevention

D Donnell, JM Baeten, NN Bumpus… - JAIDS Journal of …, 2014 - journals.lww.com
Background: Antiretroviral pre-exposure prophylaxis (PrEP) is a novel HIV prevention
strategy for which adherence is a known determinant of efficacy. Blood concentrations of …

Defining success with HIV pre-exposure prophylaxis: a prevention-effective adherence paradigm

JE Haberer, DR Bangsberg, JM Baeten, K Curran… - Aids, 2015 - journals.lww.com
To date, six clinical trials have explored the efficacy of pre-exposure prophylaxis (PrEP)
against HIV infection using oral tenofovir and/or emtricitabine/tenofovir [1–6]. Efficacy ranged …

Preexposure prophylaxis for the prevention of HIV: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, H Spencer, C Bougatsos, I Blazina, A Ahmed… - Jama, 2023 - jamanetwork.com
Importance A 2019 review for the US Preventive Services Task Force (USPSTF) found oral
preexposure prophylaxis (PrEP) associated with decreased HIV infection risk vs placebo or …

Advances in long-acting slow effective release antiretroviral therapies for treatment and prevention of HIV infection

MU Nayan, B Sillman, M Hasan, S Deodhar… - Advanced Drug Delivery …, 2023 - Elsevier
Adherence to daily oral antiretroviral therapy (ART) is a barrier to both treatment and
prevention of human immunodeficiency virus (HIV) infection. To overcome limitations of life …

Retention in care outcomes for HIV pre‐exposure prophylaxis implementation programmes among men who have sex with men in three US cities

PA Chan, L Mena, R Patel… - Journal of the …, 2016 - Wiley Online Library
Introduction Despite the efficacy of pre‐exposure prophylaxis (PrEP) in preventing HIV
transmission, few studies have evaluated PrEP use and retention in care outcomes in real …

Integrated delivery of antiretroviral treatment and pre-exposure prophylaxis to HIV-1–serodiscordant couples: a prospective implementation study in Kenya and …

JM Baeten, R Heffron, L Kidoguchi, NR Mugo… - PLoS …, 2016 - journals.plos.org
Background Antiretroviral-based interventions for HIV-1 prevention, including antiretroviral
therapy (ART) to reduce the infectiousness of HIV-1 infected persons and pre-exposure …

Extended-duration MK-8591-eluting implant as a candidate for HIV treatment and prevention

SE Barrett, RS Teller, SP Forster, L Li… - Antimicrobial agents …, 2018 - journals.asm.org
Regimen adherence remains a major hurdle to the success of daily oral drug regimens for
the treatment and prevention of human immunodeficiency virus (HIV) infection. Long-acting …