Highlights•Biocomputation refers to regulation of gene expression with machine-like
precision.•Computational networks can comprise single or multiple layers of regulation …

Artificial neural networks provide a powerful paradigm for nonbiological information
processing. To understand whether similar principles could enable computation within living …

Hypertensive vascular disease (HVD) is a major health burden globally and is a comorbidity
commonly associated with other metabolic diseases. Many factors are associated with HVD …

Inflammasomes are defense complexes that utilize cytokines and immunogenic cell death
(ICD) to stimulate the immune system against pathogens. Inspired by their dual action, we …

Protein circuit design is still in its infancy in terms of programmability. DNA nanotechnology,
however, excels at this property and its community has created a myriad of circuits and …

Background: Bladder cancer poses a significant threat to human health. In recent years,
genetic circuit therapy has emerged as a novel alternative for precision tumor treatment …

The ciliate Tetrahymena thermophila's seven mating types are defined by unique receptor-
ligand pairs (Mta/Mtb). While Mta and Mtb are known to participate in a mating signal …

Synthetic biology represents a groundbreaking frontier in biotechnological innovation,
empowering researchers to design and construct genetic and protein networks with a level …