Key Clinical Points Rosacea Rosacea is a common, chronic facial skin disease that can
have an adverse effect on quality of life; it affects more women than men. The diagnosis is …

Long considered both physiologic and inevitable, skin aging is a degenerative phenomenon
whereby both intrinsic and environmental factors conspire to produce an authentic disease …

Written by experienced and internationally renowned contributors, this is the fourth edition of
what has become the standard reference for cosmetic scientists and dermatologists seeking …

Management of melasma is highly challenging due to inconsistent treatment results and
frequent relapses. However, recent studies revealed that melasma may not only be a …

Inflammation and the resulting accumulation of reactive oxygen species (ROS) play an
important role in the intrinsic and photoaging of human skin in vivo. Environmental insults …

Melasma is a commonly acquired hypermelanosis that affects sun-exposed areas of the
skin, with frequent facial involvement. Its histologic manifestations are evident in the …

Aging is a complex, multifactorial process resulting in several functional and esthetic
changes in the skin. These changes result from intrinsic as well as extrinsic processes, such …

Cutaneous aging is a complex biological phenomenon affecting the different constituents of
the skin. To compare the effects of intrinsic and extrinsic aging processes, a total of 83 …

As the population ages, common skin disorders of the elderly demand greater attention.
Moreover, the many clinical, histologic, and physiologic changes that characterize old skin …

The skin is increasingly exposed to ambient UV-irradiation thus increasing its risk for
photooxidative damage with longterm detrimental effects like photoaging, which is …