Ion channels in cancer: are cancer hallmarks oncochannelopathies?

N Prevarskaya, R Skryma, Y Shuba - Physiological reviews, 2018‏ - journals.physiology.org
Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

[HTML][HTML] Ion channel expression as promising cancer biomarker

E Lastraioli, J Iorio, A Arcangeli - Biochimica et Biophysica Acta (BBA) …, 2015‏ - Elsevier
Cancer is a disease with marked heterogeneity in both response to therapy and survival.
Clinical and histopathological characteristics have long determined prognosis and therapy …

Intracellular chloride channels: novel biomarkers in diseases

S Gururaja Rao, NJ Patel, H Singh - Frontiers in physiology, 2020‏ - frontiersin.org
Ion channels are integral membrane proteins present on the plasma membrane as well as
intracellular membranes. In the human genome, there are more than 400 known genes …

Treatment strategies in diffuse midline gliomas with the H3K27M mutation: the role of convection-enhanced delivery in overcoming anatomic challenges

BT Himes, L Zhang, DJ Daniels - Frontiers in oncology, 2019‏ - frontiersin.org
Diffuse midline gliomas harboring the H3 K27M mutation—including the previously named
diffuse intrinsic pontine glioma (DIPG)—are lethal high-grade pediatric brain tumors that are …

Voltage-dependent anion channel 1 as an emerging drug target for novel anti-cancer therapeutics

V Shoshan-Barmatz, Y Krelin… - Frontiers in …, 2017‏ - frontiersin.org
Cancer cells share several properties, high proliferation potential, reprogramed metabolism,
and resistance to apoptotic cues. Acquiring these hallmarks involves changes in key …

[PDF][PDF] Microarray bioinformatics in cancer-a review

Z Tao, A Shi, R Li, Y Wang, X Wang, J Zhao - J buon, 2017‏ - jbuon.com
Bioinformatics is one of the newest fields of biological research, and should be viewed
broadly as the use of mathematical, statistical, and computational methods for the …

[HTML][HTML] TRPM channels in human diseases

I Jimenez, Y Prado, F Marchant, C Otero, F Eltit… - Cells, 2020‏ - mdpi.com
The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …

Prognostic and predictive values of CDK1 and MAD2L1 in lung adenocarcinoma

YX Shi, T Zhu, T Zou, W Zhuo, YX Chen… - …, 2016‏ - pmc.ncbi.nlm.nih.gov
Lung cancer remains as the leading cause of cancer-related death worldwide, and lung
adenocarcinoma (LUAD) is the most common histological subtype. This study aims to …

Bioelectric control of metastasis in solid tumors

SL Payne, M Levin, MJ Oudin - Bioelectricity, 2019‏ - liebertpub.com
As the leading cause of death in cancer, there is an urgent need to develop treatments to
target the dissemination of primary tumor cells to secondary organs, known as metastasis …

[HTML][HTML] Electrolyte disorders in cancer patients: a systematic review

R Berardi, M Torniai, E Lenci, F Pecci… - Journal of Cancer …, 2019‏ - oaepublish.com
Electrolyte disorders are very common complications in cancer patients. They might be
associated to a worsening outcome, influencing quality of life, possibility to receive …