Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

Ion channels are integral membrane proteins present on the plasma membrane as well as
intracellular membranes. In the human genome, there are more than 400 known genes …

Cancer is a disease with marked heterogeneity in both response to therapy and survival.
Clinical and histopathological characteristics have long determined prognosis and therapy …

The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …

Cancer cells share several properties, high proliferation potential, reprogramed metabolism,
and resistance to apoptotic cues. Acquiring these hallmarks involves changes in key …

Lung cancer remains as the leading cause of cancer-related death worldwide, and lung
adenocarcinoma (LUAD) is the most common histological subtype. This study aims to …

Bioinformatics is one of the newest fields of biological research, and should be viewed
broadly as the use of mathematical, statistical, and computational methods for the …

Electrolyte disorders are very common complications in cancer patients. They might be
associated to a worsening outcome, influencing quality of life, possibility to receive …

As the leading cause of death in cancer, there is an urgent need to develop treatments to
target the dissemination of primary tumor cells to secondary organs, known as metastasis …

Bioelectronic medicine is a treatment modality that uses electricity to treat disease by
altering the body's electrical communication systems. All cells are electrically active, in that …