A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection

DG Augusto, LD Murdolo, DSM Chatzileontiadou… - Nature, 2023 - nature.com
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …

HLA variation and SARS-CoV-2 specific antibody response

D Wolday, CYJ Fung, G Morgan, S Casalino… - Viruses, 2023 - mdpi.com
Differences in SARS-CoV-2-specific immune responses have been observed between
individuals following natural infection or vaccination. In addition to already known factors …

Hypocortisolemic ASIA: a vaccine-and chronic infection-induced syndrome behind the origin of long COVID and myalgic encephalomyelitis

M Ruiz-Pablos, B Paiva, A Zabaleta - Frontiers in Immunology, 2024 - frontiersin.org
Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), long COVID (LC) and
post-COVID-19 vaccine syndrome show similarities in their pathophysiology and clinical …

[HTML][HTML] Impact of SARS-CoV-2 exposure history on the T cell and IgG response

R Keeton, MB Tincho, A Suzuki, N Benede… - Cell Reports …, 2023 - cell.com
Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposures, from
infection or vaccination, can potently boost spike antibody responses. Less is known about …

Systems-level profiling of early peripheral host-response landscape variations across COVID-19 severity states in an Indian cohort

U Banerjee, S Chunchanur, KN Balaji, A Singh… - Genes & …, 2023 - nature.com
Host immune response to COVID-19 plays a significant role in regulating disease severity.
Although big data analysis has provided significant insights into the host biology of COVID …

The humoral and cellular response to mRNA SARS‐CoV‐2 vaccine is influenced by HLA polymorphisms

FE Bertinetto, P Magistroni, GA Mazzola, C Costa… - HLA, 2023 - Wiley Online Library
Host genetic variability contributes to susceptibility to SARS‐CoV‐2 infection and COVID‐19
evolution and the role of HLA system has not clearly emerged, suggesting the involvement …

Molecular mimicry and HLA polymorphisms may drive autoimmunity in recipients of the BNT-162b2 mRNA vaccine: a computational analysis

R Talotta - Microorganisms, 2023 - mdpi.com
Background: After the start of the worldwide COVID-19 vaccination campaign, there were
increased reports of autoimmune diseases occurring de novo after vaccination. This in silico …

Adult risk groups for vaccine preventable respiratory infections: an overview of the UK environment

C Reynard, J Campling, AL Gordon… - Expert Review of …, 2024 - Taylor & Francis
Introduction Vaccine-preventable respiratory infections (VPRI) including those caused by
Streptococcus pneumoniae, influenza, respiratory syncytial virus and severe acute …

Molecular Understanding of ACE-2 and HLA-conferred differential susceptibility to COVID-19: host-directed insights opening new windows in COVID-19 Therapeutics

IU Haq, K Krukiewicz, H Tayyab, I Khan… - Journal of Clinical …, 2023 - mdpi.com
The genetic variants of HLAs (human leukocyte antigens) play a crucial role in the virus–
host interaction and pathology of COVID-19. The genetic variants of HLAs not only influence …

Genetic determinants of IgG antibody response to COVID-19 vaccination

S Bian, X Guo, X Yang, Y Wei, Z Yang, S Cheng… - The American Journal of …, 2024 - cell.com
Human humoral immune responses to SARS-CoV-2 vaccines exhibit substantial inter-
individual variability and have been linked to vaccine efficacy. To elucidate the underlying …