Regeneration in the animal kingdom is one of the most fascinating problems that have
allowed scientists to address many issues of fundamental importance in basic biology …

Spinal cord injury results in permanent sensorimotor loss in mammals, in part due to a lack
of injury-induced neurogenesis. The regeneration of neurons depends upon resident neural …

Radial glial cells are presumptive neural stem cells (NSCs) in the develo** nervous
system. The direct requirement of radial glia for the generation of a diverse array of neuronal …

In mammals, spinal cord injury results in permanent sensory–motor loss due in part to a
failure in reinitiating local neurogenesis. However, zebrafish show robust neuronal …

The subventricular zone (SVZ) is a neurogenic niche that contributes to homeostasis and
repair after brain injury. However, the effects of mild traumatic brain injury (mTBI) on the …

Abstract 2′, 2′, 4, 4′-tetrabromo diphenyl ether (BDE-47), one of the most abundant
congeners of commercial pentaBDE utilized as flame retardants, has been phased out of …

Neural stem cells (NSCs) are self-renewing, multipotent and undifferentiated precursors that
retain the capacity for differentiation into both glial and neuronal lineages. MicroRNAs …

The Lef/Tcf-family transcription factor Tcf3 has important roles in development, stem cell
function and malignancy. Previous gain-and loss-of-function studies have suggested that …

The transcription factor Sox4 plays an indispensable role in the development of early
progenitor B cells from hematopoietic stem cells. However, its role in B-cell acute …

Introduction Mouse fibroblasts could be directly converted into induced neural stem cells
(iNSCs), by introducing a set of known transcription factors (TFs). This process, known as …