• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The present critical review was conducted to evaluate the clinimetric properties of the
Charlson Comorbidity Index (CCI), an assessment tool designed specifically to predict long …

Infective endocarditis in children is a rare entity that poses multiple challenges. A history of
congenital heart disease is the most common risk factor, although in recent years, other …

Infective endocarditis is a relatively rare, but deadly cause of sepsis, with an overall mortality
ranging from 20 to 25% in most series. Although the classic clinical classification into …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Background Most published reports describing outcomes of patients with cardiovascular
implantable electronic device–related infective endocarditis (CIED‐IE) are single‐center …

The specific management of infective endocarditis (IE) in elderly patients is not specifically
addressed in recent guidelines despite its increasing incidence and high mortality in this …

Background Our aim was to compare pediatric infective endocarditis (IE) with the clinical
profile and outcomes of IE in adults. Methods Prospective multicenter registry in 31 Spanish …

Background Infective endocarditis (IE) is increasingly affecting older patients. However, data
on their management are sparse, and the benefits of surgery in this population are unclear …

Aims Patients with infective endocarditis (IE) frequently have cardiac implantable electronic
devices (CIEDs). Here, we aim to define the clinical profile and prognostic factors of IE in …