Ten years of anti-vascular endothelial growth factor therapy

N Ferrara, AP Adamis - Nature reviews Drug discovery, 2016 - nature.com
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

Molecular pathogenesis of retinal and choroidal vascular diseases

PA Campochiaro - Progress in retinal and eye research, 2015 - Elsevier
There are two major types of ocular neovascularization that affect the retina, retinal
neovascularization (NV) and subretinal or choroidal NV. Retinal NV occurs in a group of …

Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions

I Klaassen, CJF Van Noorden… - Progress in retinal and …, 2013 - Elsevier
Breakdown of the inner endothelial blood-retinal barrier (BRB), as occurs in diabetic
retinopathy, age-related macular degeneration, retinal vein occlusions, uveitis and other …

Mechanisms and management of retinopathy of prematurity

ME Hartnett, JS Penn - New England Journal of Medicine, 2012 - Mass Medical Soc
Mechanisms and Management of Retinopathy of Prematurity | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

The biology of VEGF and its receptors

N Ferrara, HP Gerber, J LeCouter - Nature medicine, 2003 - nature.com
Vascular endothelial growth factor (VEGF) is a key regulator of physiological angiogenesis
during embryogenesis, skeletal growth and reproductive functions. VEGF has also been …

[PDF][PDF] Microvascular and macrovascular complications of diabetes

MJ Fowler - Clinical diabetes, 2008 - cmbdiabetes.wdfiles.com
Diabetes is a group of chronic diseases characterized by hyperglycemia. Modern medical
care uses a vast array of lifestyle and pharmaceutical interventions aimed at preventing and …

The biology of vascular endothelial growth factor

N Ferrara, T Davis-Smyth - Endocrine reviews, 1997 - academic.oup.com
Biology of Vascular Endothelial Growth Factor | Endocrine Reviews | Oxford Academic Skip to
Main Content Advertisement Oxford Academic Journals Books Search Menu Information …

Anti‐vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity

MJ Sankar, J Sankar, P Chandra - Cochrane Database of …, 2018 - cochranelibrary.com
Background Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis in
foetal life. Researchers have recently attempted to use anti‐VEGF agents for the treatment of …

Vascular endothelial growth factor: basic science and clinical progress

N Ferrara - Endocrine reviews, 2004 - academic.oup.com
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

Design, clinical translation and immunological response of biomaterials in regenerative medicine

K Sadtler, A Singh, MT Wolf, X Wang… - Nature Reviews …, 2016 - nature.com
The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …