Serine protease inhibitor AEBSF (4-(2-aminoethyl)-benzenesulfonyl fluoride) decreased ischemic brain injury through inhibiting endoplasmic reticulum stress …

Q An, Y Zhu, W Shi, W Li, X Yang, M Huang, Y Li… - Brain Research, 2025‏ - Elsevier
(2-Aminoethyl)-benzenesulfonyl fluoride (AEBSF) is a serine protease inhibitor that may
alleviate endoplasmic reticulum (ER) stress, a significant contributing factor to cerebral …

Neuroprotective Role of Da Qin Jiu Decoction in Ischemic Stroke: Mitochondrial Rescue through PI3K/Akt-Mediated UPRmt Activation

J Luo, Y Zheng, J Chen, X **ong, J Shen… - Journal of …, 2025‏ - Elsevier
Abstract Ethnopharmacological Relevance Ischemic stroke (IS) is a highly debilitating
neurological condition with limited treatment options and suboptimal outcomes. The …

[HTML][HTML] Enhancement of Mitochondrial Homeostasis: A Novel Approach to Attenuate Hypoxic Myocardial Injury

Z Guo, Y Tian, J Gao, B Zhou, XT Zhou… - … Journal of Medical …, 2024‏ - pmc.ncbi.nlm.nih.gov
Cardiomyocytes are highly oxygen-dependent cells, relying on oxygen-driven oxidative
phosphorylation to maintain their function. During hypoxia, mitochondrial ATP production …