Mortality after bleeding versus myocardial infarction in coronary artery disease: a systematic review and meta-analysis: Mortality after bleeding vs MI in CAD patients

R Piccolo, A Oliva, M Avvedimento… - …, 2021 - pmc.ncbi.nlm.nih.gov
Background Bleeding is the principal safety concern of antithrombotic therapy and occurs
frequently among patients with coronary artery disease (CAD). Aims We aimed to evaluate …

Validation of the academic research consortium high bleeding risk definition in contemporary PCI patients

D Cao, R Mehran, G Dangas, U Baber, S Sartori… - Journal of the American …, 2020 - jacc.org
Background Bleeding following percutaneous coronary intervention has important
prognostic implications. The Academic Research Consortium (ARC) recently proposed a list …

Incidence, predictors, and impact of post-discharge bleeding after percutaneous coronary intervention

P Généreux, G Giustino, B Witzenbichler… - Journal of the American …, 2015 - jacc.org
Background: The incidence, predictors, and prognostic impact of post-discharge bleeding
(PDB) after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) …

Trade-off of myocardial infarction vs. bleeding types on mortality after acute coronary syndrome: lessons from the Thrombin Receptor Antagonist for Clinical Event …

M Valgimigli, F Costa, Y Lokhnygina… - European heart …, 2017 - academic.oup.com
Aims Dual antiplatelet therapy reduces non-fatal ischaemic events after acute coronary
syndrome (ACS) but increases bleeding to a similar extent. We sought to determine the …

Clinical outcomes of concomitant use of proton pump inhibitors and dual antiplatelet therapy: a systematic review and meta-analysis

H Guo, Z Ye, R Huang - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: The safety and efficacy associated with the use of proton pump inhibitors (PPIs)
by patients with coronary artery disease receiving dual antiplatelet therapy (DAPT) remain …

3-or 1-month DAPT in patients at high bleeding risk undergoing everolimus-eluting stent implantation

R Mehran, D Cao, DJ Angiolillo, S Bangalore… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this study was to evaluate 2 abbreviated dual-antiplatelet therapy
(DAPT) regimens in patients at high bleeding risk (HBR) undergoing percutaneous coronary …

Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome: Network Meta-Analysis of 52 816 Patients From 12 Randomized Trials

EP Navarese, SU Khan, M Kołodziejczak, J Kubica… - Circulation, 2020 - ahajournals.org
Background: New randomized, controlled trials have become available on oral P2Y12
inhibitors in acute coronary syndrome. We aimed to evaluate current evidence comparing …

Assessing the risks of bleeding vs thrombotic events in patients at high bleeding risk after coronary stent implantation: the ARC–high bleeding risk trade-off model

P Urban, J Gregson, R Owen, R Mehran… - JAMA …, 2021 - jamanetwork.com
Importance Patients who are candidates for percutaneous coronary intervention (PCI) and
are at high bleeding risk constitute a therapeutic challenge because they often also face an …

Bleeding-related deaths in relation to the duration of dual-antiplatelet therapy after coronary stenting

T Palmerini, L Bacchi Reggiani, D Della Riva… - Journal of the American …, 2017 - jacc.org
Background: Although some randomized controlled trials (RCTs) and meta-analyses have
suggested that prolonged dual-antiplatelet therapy (DAPT) may be associated with …

Reduced risk of gastrointestinal bleeding associated with proton pump inhibitor therapy in patients treated with dual antiplatelet therapy after myocardial infarction

TSG Sehested, N Carlson, PW Hansen… - European Heart …, 2019 - academic.oup.com
Aims Guidelines differ in their recommendations on therapy to prevent gastrointestinal
bleeding for patients treated with dual antiplatelet treatment (DAPT). We sought to …