Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre) clinical studies
BM Privé, MA Boussihmad, B Timmermans… - European journal of …, 2023 - Springer
Introduction Fibroblast activation protein (FAP) is highly overexpressed in stromal tissue of
various cancers. While FAP has been recognized as a potential diagnostic or therapeutic …
various cancers. While FAP has been recognized as a potential diagnostic or therapeutic …
Comparison of Radionuclide Drug Conjugates With Boron Neutron Capture Therapy: An Overview of Targeted Charged Particle Radiation Therapy
Y Zhang, P Coghi, Z Ren… - Medicinal Research …, 2024 - Wiley Online Library
Targeted charged alpha‐and beta‐particle therapies are currently being used in clinical
radiation treatments as newly developed methods for either killing or controlling tumor cell …
radiation treatments as newly developed methods for either killing or controlling tumor cell …
Diagnostic performances of PET/CT using fibroblast activation protein inhibitors in patients with primary and metastatic liver tumors: a Comprehensive Literature …
F Manuppella, G Pisano, S Taralli, C Caldarella… - International Journal of …, 2024 - mdpi.com
PET/CT using radiolabeled fibroblast activation protein inhibitors (FAPIs) is a promising
diagnostic tool in oncology, especially when non-increased and/or physiologically high [18F] …
diagnostic tool in oncology, especially when non-increased and/or physiologically high [18F] …
Clinical applications of fibroblast activation protein‐targeted theranostics in oncologic and nononcologic disease: Current status and future directions
H Fu, W Guo, J Huang, H Wu, H Chen - iRADIOLOGY, 2023 - Wiley Online Library
Quinoline‐based fibroblast activation protein (FAP) inhibitor (FAPI)‐based positron emission
tomography (PET) imaging and radioligand therapy (RLT) are being investigated for use in a …
tomography (PET) imaging and radioligand therapy (RLT) are being investigated for use in a …
放射性核素治疗药物的临床研究进展
刘嘉月， 郭晓轶， 朱华， 杨志 - 药学进展, 2024 - pps.cpu.edu.cn
放射性核素治疗(RNT) 系将放射性核素聚集在病变部位, 利用电离辐射生物效应杀伤病变组织.
钇-90 (90 Y), 镥-177 (177 Lu), 铽-161 (161 Tb) 是**年来备受关注的β 射线核素, 也是RNT …
钇-90 (90 Y), 镥-177 (177 Lu), 铽-161 (161 Tb) 是**年来备受关注的β 射线核素, 也是RNT …
Variable tracer avidity and interlesional heterogeneity on 18F-FDG, 68Ga-DOTATATE, and 68Ga-DOTA-FAPi-04 PET/CT imaging in a single individual patient with …
Y Edamadaka, RV Parghane, S Basu - Clinical Nuclear Medicine, 2024 - journals.lww.com
In medullary thyroid carcinoma (MTC), distant metastases have few therapeutic options with
low success rates and substantial toxicity in many patients, warranting exploration of …
low success rates and substantial toxicity in many patients, warranting exploration of …
Endocrine system
X Lu, Y Zhu, T Zhu - Adverse Effects of Engineered Nanomaterials, 2017 - Elsevier
The two major systems responsible for body control and communication are the neurological
system and the endocrine system. The endocrine organs release hormones, which travel …
system and the endocrine system. The endocrine organs release hormones, which travel …
False-Negative 68Ga-FAPI PET/CT in Pediatric Thyroid Medullary Carcinoma Seen With 68Ga-DOTATOC PET/CT and 18F-FDG PET/CT
MB Haidar, FA Abou Zeid, ZZ Meguerian… - Clinical Nuclear …, 2024 - journals.lww.com
In adults, 68 Ga-FAP inhibitor (68 Ga-FAPI) PET/CT outperforms 68 Ga-radiolabeled
somatostatin analog peptides (68 Ga PET/CT) and 18 F-FDG PET/CT in detecting thyroid …
somatostatin analog peptides (68 Ga PET/CT) and 18 F-FDG PET/CT in detecting thyroid …
99mTc-HYNIC-FAPI-46 SPECT/CT Uptake in Lactating Breasts
B Hadad, K Aryana, H Kamali… - Clinical Nuclear Medicine, 2022 - journals.lww.com
A 36-year-old woman with a history of medullary thyroid carcinoma was referred for 99m Tc-
HYNIC-FAPI-46 scan. Her calcitonin levels gradually increased after external beam …
HYNIC-FAPI-46 scan. Her calcitonin levels gradually increased after external beam …
靶向成纤维细胞激活蛋白放射性药物在恶性肿瘤诊疗中的研究进展
**梦婷， 兰晓莉， 江大卫 - 药学进展, 2023 - pps.cpu.edu.cn
**年来, 靶向成纤维细胞激活蛋白(FAP) 的放射性药物在恶性肿瘤诊疗一体化领域备受关注.
FAP 是一种表达于肿瘤间质的蛋白质, 在肿瘤进展和转移过程中发挥着重要作用 …
FAP 是一种表达于肿瘤间质的蛋白质, 在肿瘤进展和转移过程中发挥着重要作用 …