Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …

Atherosclerosis (AS) is an inflammatory disease linked to endothelial dysfunction. Melatonin
is reported to possess substantial anti‐inflammatory properties, which has proven to be …

Atherosclerosis-associated cardiovascular disease is one of the main causes of death and
disability among patients with diabetes mellitus. However, little is known about the impact of …

Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …

Vascular endothelial dysfunction (VED) and inflammation contribute to the initiation and
progression of atherosclerosis. Melatonin (MLT) normalizes lipid profile, improves …

Melanopsin-containing retinal ganglion cells (mRGCs) represent a third class of retinal
photoreceptors involved in regulating the pupillary light reflex and circadian …

Saffron, an extract from Crocus sativus, has been largely used in traditional medicine for its
antiapoptotic and anticarcinogenic properties. In this work, we investigate the effects of …

Purpose.: To evaluate the preventive effect of tauroursodeoxycholic acid (TUDCA) on
photoreceptor degeneration, synaptic connectivity and functional activity of the retina in the …

The confinement of critically ill patients in intensive care units (ICU) imposes environmental
constancy throughout both day and night (continuous light, noise, caring activities …