Tailoring gelation mechanisms for advanced hydrogel applications

V Nele, JP Wojciechowski… - Advanced Functional …, 2020 - Wiley Online Library
Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

[HTML][HTML] Thiolated polymeric hydrogels for biomedical application: Cross-linking mechanisms

S Summonte, GF Racaniello, A Lopedota… - Journal of Controlled …, 2021 - Elsevier
This review focuses on the synthesis of hydrogel networks using thiomers such as thiolated
hyaluronic acid, chitosan, cyclodextrin, poly (ethylene glycol) and dextran that are cross …

Green light triggered [2+ 2] cycloaddition of halochromic styrylquinoxaline—controlling photoreactivity by pH

K Kalayci, H Frisch, VX Truong… - Nature …, 2020 - nature.com
Photochemical reactions are a powerful tool in (bio) materials design due to the spatial and
temporal control light can provide. To extend their applications in biological setting, the use …

Star polymer networks: a toolbox for cross-linked polymers with controlled structure

S Nakagawa, N Yoshie - Polymer Chemistry, 2022 - pubs.rsc.org
The synthesis of precisely controlled polymer networks has been a long-cherished dream of
polymer scientists. Traditional random cross-linking strategies often lead to uncontrolled …

Chemical and biological engineering strategies to make and modify next-generation hydrogel biomaterials

R Gharios, RM Francis, CA DeForest - Matter, 2023 - cell.com
There is a growing interest in the development of technologies to probe and direct in vitro
cellular function for fundamental organoid and stem cell biology, functional tissue and …

Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties

AR Namjoo, FN Abrbekoh, S Saghati, H Amini… - Stem Cell Research & …, 2023 - Springer
Muscular diseases and injuries are challenging issues in human medicine, resulting in
physical disability. The advent of tissue engineering approaches has paved the way for the …

Assembling Complex Macromolecules and Self-Organizations of Biological Relevance with Cu (I)-Catalyzed Azide-Alkyne, Thio-Bromo, and TERMINI Double “Click” …

A Moreno, G Lligadas, J Adamson, DS Maurya… - Polymers, 2023 - mdpi.com
In 2022, the Nobel Prize in Chemistry was awarded to Bertozzi, Meldal, and Sharpless “for
the development of click chemistry and biorthogonal chemistry”. Since 2001, when the …

Green light enabled Staudinger–Bertozzi ligation

K Kalayci, H Frisch, C Barner-Kowollik… - Chemical …, 2022 - pubs.rsc.org
We introduce a visible light-induced Staudinger–Bertozzi ligation via photo-uncaging of a
triphenylphosphine moiety with a photolabile coumarin derivative. Our action plot study …

Synthesis of fully degradable cationic polymers with various topological structures via postpolymerization modification by using thio-bromo “click” reaction

Y Dai, Z Hu, X Wang, X Liu, Y Li, Y Shi, Y Chen - Polymer Chemistry, 2021 - pubs.rsc.org
Synthesis of cationic polymers possessing significant therapeutic potential is of tremendous
research interest. Here, we report a facile synthesis of poly (ε-caprolactone)(PCL) based …