An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.

K Shahane, M Kshirsagar, S Tambe, D Jain, S Rout… - Pharmaceuticals, 2023‏ - mdpi.com
Calendula officinalis Linn.(CO) is a popular medicinal plant from the plant kingdom's
Asteraceae family that has been used for millennia. This plant contains flavonoids …

[HTML][HTML] Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications

S Ijaz, J Iqbal, BA Abbasi, Z Ullah, T Yaseen… - Biomedicine & …, 2023‏ - Elsevier
Cancer is still the leading cause of death worldwide, burdening the global medical system.
Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a …

Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy

J Sharifi-Rad, V Seidel, M Izabela… - Cell Communication and …, 2023‏ - Springer
Cancer is a leading cause of death worldwide and involves an oxidative stress mechanism.
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …

[HTML][HTML] Biological and bioactive components of bitter leaf (Vernonia amygdalina leaf): insight on health and nutritional benefits. A review

GI Edo, PO Samuel, AN Jikah, FO Onoharigho… - Food Chemistry …, 2023‏ - Elsevier
Recently, significant attention has been paid to the biologically active substances in plants
that aid in preventing, treating or delaying diseases brought on by inflammatory and …

Natural coumarins from two cultivars of watermelon seeds as biosafe anticancer agents, an algorithm for their isolation and evaluation

YF Mustafa, RN Ismael, RM Jebir - Journal of Molecular Structure, 2024‏ - Elsevier
The seeds of two watermelon cultivars–allsweet and princess–were explored in this study as
sources of potential biosafe natural antioxidant and anticancer agents. In the first algorithmic …

Psoralea corylifolia L.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics

L Chen, S Chen, P Sun, X Liu, Z Zhan, J Wang - Chinese medicine, 2023‏ - Springer
Abstract Psoralea corylifolia L.(PCL), referred to as “Bu-gu-zhi” in Chinese, has great
medicinal values since ancient times. PCL is the dried ripe fruit of Psoralea corylifolia L …

Antioxidant activity of coumarins and their metal complexes

L Todorov, L Saso, I Kostova - Pharmaceuticals, 2023‏ - mdpi.com
Ubiquitously present in plant life, coumarins, as a class of phenolic compounds, have
multiple applications—in everyday life, in organic synthesis, in medicine and many others …

Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease

H Zhang, Y Wang, Y Wang, X Li, S Wang… - European Journal of …, 2022‏ - Elsevier
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …

Tobacco Smoking and Liver Cancer Risk: Potential Avenues for Carcinogenesis

D Jain, P Chaudhary, N Varshney… - Journal of …, 2021‏ - Wiley Online Library
Smoking a cigarette generates over 4000 chemicals that have a deleterious impact on each
part of the human body. It produces three main severe effects on the liver organ: oncogenic …

Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs

J Popović-Djordjević, C Quispe, R Giordo… - European journal of …, 2022‏ - Elsevier
The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …