From COVID-19 to cancer mRNA vaccines: moving from bench to clinic in the vaccine landscape
Recently, mRNA vaccines have become a significant type of therapeutic and have created
new fields in the biopharmaceutical industry. mRNA vaccines are promising next-generation …
new fields in the biopharmaceutical industry. mRNA vaccines are promising next-generation …
Schizophyllan: A review on its structure, properties, bioactivities and recent developments
Y Zhang, H Kong, Y Fang, K Nishinari… - … and Dietary Fibre, 2013 - Elsevier
Since its first discovery in the late 1960s, schizophyllan attracted much attention from both
academia and industry. Schizophyllan is an exopolysaccharide elaborated by the …
academia and industry. Schizophyllan is an exopolysaccharide elaborated by the …
Endocytic profiling of cancer cell models reveals critical factors influencing LNP-mediated mRNA delivery and protein expression
Lipid nanoparticles have great potential for delivering nucleic-acid-based therapeutics, but
low efficiency limits their broad clinical translation. Differences in transfection capacity …
low efficiency limits their broad clinical translation. Differences in transfection capacity …
Progress of RAFT based polymers in gene delivery
The review provides a comprehensive account on the development of gene delivery vectors
via reversible addition-fragmentation chain transfer polymerization (RAFT) approach. Since …
via reversible addition-fragmentation chain transfer polymerization (RAFT) approach. Since …
Engineering carbohydrate-based particles for biomedical applications: strategies to construct and modify
Carbohydrate-based micro/nanoparticles have gained significant attention for various
biomedical applications such as targeted/triggered/controlled drug delivery, bioimaging …
biomedical applications such as targeted/triggered/controlled drug delivery, bioimaging …
Investigating the effects of block versus statistical glycopolycations containing primary and tertiary amines for plasmid DNA delivery
D Sprouse, TM Reineke - Biomacromolecules, 2014 - ACS Publications
Polymer composition and morphology can affect the way polymers interact with
biomolecules, cell membranes, and intracellular components. Herein, diblock, triblock, and …
biomolecules, cell membranes, and intracellular components. Herein, diblock, triblock, and …
Tailor‐made antimicrobial/antiviral star polymer via ATRP of Cyclodextrin and guanidine‐based macromonomer
Novel star‐like polymers are prepared via atom transfer radical polymerization (ATRP) of
polyhexamethylene guanidine hydrochloride (PHMG) macromonomer and acrylamide (AM) …
polyhexamethylene guanidine hydrochloride (PHMG) macromonomer and acrylamide (AM) …
Multiarm cationic star polymers by atom transfer radical polymerization from β-cyclodextrin cores: Influence of arm number and length on gene delivery
Controlled β-cyclodextrin (β-CD) core-based cationic star polymers have attracted
considerable attention as non-viral gene carriers. Atom transfer radical polymerization …
considerable attention as non-viral gene carriers. Atom transfer radical polymerization …
Lower rim guanidinocalix [4] arenes: macrocyclic nonviral vectors for cell transfection
V Bagnacani, V Franceschi, L Fantuzzi… - Bioconjugate …, 2012 - ACS Publications
Guanidinium groups were introduced through a spacer at the lower rim of calix [4] arenes in
the cone conformation to give new potential nonviral vectors for gene delivery. Several …
the cone conformation to give new potential nonviral vectors for gene delivery. Several …
A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery
Y Wang, C Li, L Du, Y Liu - Chinese Chemical Letters, 2020 - Elsevier
Nonviral vectors have been attracting more attention for several advantages in gene delivery
and the development of nonviral gene carriers with high delivery efficiency and low …
and the development of nonviral gene carriers with high delivery efficiency and low …