[HTML][HTML] Artificial intelligence in retina

U Schmidt-Erfurth, A Sadeghipour, BS Gerendas… - Progress in retinal and …, 2018 - Elsevier
Major advances in diagnostic technologies are offering unprecedented insight into the
condition of the retina and beyond ocular disease. Digital images providing millions of …

Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities

PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …

[HTML][HTML] Fully automated detection and quantification of macular fluid in OCT using deep learning

T Schlegl, SM Waldstein, H Bogunovic, F Endstraßer… - Ophthalmology, 2018 - Elsevier
Purpose Development and validation of a fully automated method to detect and quantify
macular fluid in conventional OCT images. Design Development of a diagnostic modality …

Five-year outcomes with anti–vascular endothelial growth factor treatment of neovascular age-related macular degeneration: the comparison of age-related macular …

MG Maguire, DF Martin, G Ying, GJ Jaffe, E Daniel… - Ophthalmology, 2016 - Elsevier
Purpose To describe outcomes 5 years after initiating treatment with bevacizumab or
ranibizumab for neovascular age-related macular degeneration (AMD). Design Cohort …

Tolerating subretinal fluid in neovascular age-related macular degeneration treated with ranibizumab using a treat-and-extend regimen: FLUID study 24-month results

RH Guymer, CM Markey, IL McAllister, MC Gillies… - Ophthalmology, 2019 - Elsevier
Purpose To test the hypothesis that tolerating some subretinal fluid (SRF) in patients with
neovascular age-related macular degeneration (nAMD) treated with ranibizumab using a …

A paradigm shift in imaging biomarkers in neovascular age-related macular degeneration

U Schmidt-Erfurth, SM Waldstein - Progress in Retinal and eye Research, 2016 - Elsevier
Neovascular age-related macular degeneration (AMD) has undergone substantial break-
throughs in diagnostic as well as therapeutic respect, with optical coherence tomography …

RETOUCH: The retinal OCT fluid detection and segmentation benchmark and challenge

H Bogunović, F Venhuizen, S Klimscha… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Retinal swelling due to the accumulation of fluid is associated with the most vision-
threatening retinal diseases. Optical coherence tomography (OCT) is the current standard of …

[HTML][HTML] Quantitative analysis of OCT for neovascular age-related macular degeneration using deep learning

G Moraes, DJ Fu, M Wilson, H Khalid, SK Wagner… - Ophthalmology, 2021 - Elsevier
Purpose To apply a deep learning algorithm for automated, objective, and comprehensive
quantification of optical coherence tomography (OCT) scans to a large real-world dataset of …

[HTML][HTML] Application of automated quantification of fluid volumes to anti–VEGF therapy of neovascular age-related macular degeneration

U Schmidt-Erfurth, WD Vogl, LM Jampol, H Bogunović - Ophthalmology, 2020 - Elsevier
Purpose Anti–vascular endothelial growth factor (VEGF) treatment of neovascular age-
related macular degeneration (AMD) is a highly effective advance in the retinal armentarium …

Macular morphology and visual acuity in the second year of the comparison of age-related macular degeneration treatments trials

S Sharma, CA Toth, E Daniel, JE Grunwald… - Ophthalmology, 2016 - Elsevier
Purpose To describe the association between morphologic features on fundus photography
(FP), fluorescein angiography (FA), and optical coherence tomography (OCT) and visual …