Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …
Iron in neurodegeneration–cause or consequence?
A Ndayisaba, C Kaindlstorfer… - Frontiers in neuroscience, 2019 - frontiersin.org
Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions.
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …
[HTML][HTML] Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives
Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …
and dementia worldwide. The pathobiology of the disease has been studied in the form of …
Oxidative stress and the pathogenesis of Alzheimer′ s disease
Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)
It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …
Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
The adverse effects of air pollution on the nervous system
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)
The basic role of metal ions including copper, zinc and iron in neurological pathologies is
generally accepted. The relationship between the development of disease and particular …
generally accepted. The relationship between the development of disease and particular …
Fluorescence imaging of metal ions implicated in diseases
X Qian, Z Xu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal ions play an important role in various biological processes, their abnormal
homeostasis in cells is related to many diseases, such as neurodegenerative disease …
homeostasis in cells is related to many diseases, such as neurodegenerative disease …
Carbon nanodots prepared from o-phenylenediamine for sensing of Cu 2+ ions in cells
A simple hydrothermal method was applied to prepare carbon nanodots (C dots) from o-
phenylenediamine (OPD). The C dots exhibit photoluminescence at 567 nm when excited at …
phenylenediamine (OPD). The C dots exhibit photoluminescence at 567 nm when excited at …