Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Target identification for small bioactive molecules: finding the needle in the haystack

S Ziegler, V Pries, C Hedberg… - Angewandte Chemie …, 2013 - Wiley Online Library
Identification and confirmation of bioactive small‐molecule targets is a crucial, often decisive
step both in academic and pharmaceutical research. Through the development and …

Marine natural products: a new wave of drugs?

R Montaser, H Luesch - Future medicinal chemistry, 2011 - Taylor & Francis
The largely unexplored marine world that presumably harbors the most biodiversity may be
the vastest resource to discover novel 'validated'structures with novel modes of action that …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2011 - pubs.rsc.org
Covering: 2009. Previous review: Nat. Prod. Rep., 2010, 27, 165 This review covers the
literature published in 2009 for marine natural products, with 857 citations (588 for the …

Divergent Synthesis of [3,4]-Fused 3-Alkenyl-Oxindoles via Propargyl Alcohol-Triggered C(sp3)–H Functionalization

F Hu, X Li, Z Ding, L Wang, C Ge, L Xu, SS Li - ACS Catalysis, 2021 - ACS Publications
[3, 4]-Fused oxindoles are the core structures of the naturally occurring oxindole alkaloids,
and the fused tricyclic structures have distinguished themselves with unique biological …

The essentials of marine biotechnology

A Rotter, M Barbier, F Bertoni, AM Bones… - Frontiers In marine …, 2021 - frontiersin.org
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …

Biologically active quinoline and quinazoline alkaloids part II

XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …

Recent advances in deep-sea natural products

D Skropeta, L Wei - Natural product reports, 2014 - pubs.rsc.org
Covering: 2009 to 2013. This review covers the 188 novel marine natural products
described since 2008, from deep-water (50–> 5000 m) marine fauna including bryozoa …

Nonenzymatic reactions in natural product formation

LM Bouthillette, V Aniebok, DA Colosimo… - Chemical …, 2022 - ACS Publications
Biosynthetic mechanisms of natural products primarily depend on systems of protein
catalysts. However, within the field of biosynthesis, there are cases in which the inherent …

3‐alkenyl‐oxindoles: natural products, pharmaceuticals, and recent synthetic advances in tandem/telescoped approaches

A Millemaggi, RJK Taylor - European Journal of Organic …, 2010 - Wiley Online Library
The structures and biological activities of naturally occurring 3‐alkenyl‐oxindoles are
reviewed. Important man‐made3‐alkenyl‐oxindoles are covered, particularly those with …