Mechanism of action of ribosomally synthesized and post-translationally modified peptides
C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …
product class that has undergone significant expansion due to the rapid growth in genome …
Target identification for small bioactive molecules: finding the needle in the haystack
S Ziegler, V Pries, C Hedberg… - Angewandte Chemie …, 2013 - Wiley Online Library
Identification and confirmation of bioactive small‐molecule targets is a crucial, often decisive
step both in academic and pharmaceutical research. Through the development and …
step both in academic and pharmaceutical research. Through the development and …
Marine natural products: a new wave of drugs?
The largely unexplored marine world that presumably harbors the most biodiversity may be
the vastest resource to discover novel 'validated'structures with novel modes of action that …
the vastest resource to discover novel 'validated'structures with novel modes of action that …
Marine natural products
Covering: 2009. Previous review: Nat. Prod. Rep., 2010, 27, 165 This review covers the
literature published in 2009 for marine natural products, with 857 citations (588 for the …
literature published in 2009 for marine natural products, with 857 citations (588 for the …
Divergent Synthesis of [3,4]-Fused 3-Alkenyl-Oxindoles via Propargyl Alcohol-Triggered C(sp3)–H Functionalization
F Hu, X Li, Z Ding, L Wang, C Ge, L Xu, SS Li - ACS Catalysis, 2021 - ACS Publications
[3, 4]-Fused oxindoles are the core structures of the naturally occurring oxindole alkaloids,
and the fused tricyclic structures have distinguished themselves with unique biological …
and the fused tricyclic structures have distinguished themselves with unique biological …
The essentials of marine biotechnology
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …
Biologically active quinoline and quinazoline alkaloids part II
XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …
Recent advances in deep-sea natural products
D Skropeta, L Wei - Natural product reports, 2014 - pubs.rsc.org
Covering: 2009 to 2013. This review covers the 188 novel marine natural products
described since 2008, from deep-water (50–> 5000 m) marine fauna including bryozoa …
described since 2008, from deep-water (50–> 5000 m) marine fauna including bryozoa …
Nonenzymatic reactions in natural product formation
LM Bouthillette, V Aniebok, DA Colosimo… - Chemical …, 2022 - ACS Publications
Biosynthetic mechanisms of natural products primarily depend on systems of protein
catalysts. However, within the field of biosynthesis, there are cases in which the inherent …
catalysts. However, within the field of biosynthesis, there are cases in which the inherent …
3‐alkenyl‐oxindoles: natural products, pharmaceuticals, and recent synthetic advances in tandem/telescoped approaches
A Millemaggi, RJK Taylor - European Journal of Organic …, 2010 - Wiley Online Library
The structures and biological activities of naturally occurring 3‐alkenyl‐oxindoles are
reviewed. Important man‐made3‐alkenyl‐oxindoles are covered, particularly those with …
reviewed. Important man‐made3‐alkenyl‐oxindoles are covered, particularly those with …