[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery

A Khosa, S Reddi, RN Saha - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …

Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease

P Saha, H Kathuria, MM Pandey - Journal of Controlled Release, 2023 - Elsevier
Parkinson's disease (PD) is the second leading neurodegenerative disease globally,
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …

Development of carbamazepine nanostructured lipid carrier loaded thermosensitive gel for intranasal delivery

SS Deshkar, MS Jadhav… - Advanced …, 2020 - pmc.ncbi.nlm.nih.gov
Purpose: The present research work was designed to formulate and evaluate
carbamazepine (CBZ) loaded nanostructured lipid carrier (NLC) based in-situ gel for nasal …

Silibinin-loaded nanostructured lipid carriers (NLCs) ameliorated cognitive deficits and oxidative damages in aluminum chloride-induced neurotoxicity in male mice

S Makhdoomi, MM Mahboobian, R Haddadi, A Komaki… - Toxicology, 2022 - Elsevier
Aluminum chloride (AlCl3) and its accumulation in the brain are associated with
neurodegenerative disease. Recent investigations have illustrated that silibinin is known to …

Nanostructured lipid carriers for improved delivery of therapeutics via the oral route

AK Mahor, PP Singh, R Gupta… - Journal of …, 2023 - Wiley Online Library
Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid‐
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …

Advances in BBB on chip and application for studying reversible opening of blood–brain barrier by sonoporation

Y Cai, K Fan, J Lin, L Ma, F Li - Micromachines, 2022 - mdpi.com
The complex structure of the blood–brain barrier (BBB), which blocks nearly all large
biomolecules, hinders drug delivery to the brain and drug assessment, thus decelerating …

Design and in vivo evaluation of solid lipid nanoparticulate systems of Olanzapine for acute phase schizophrenia treatment: Investigations on antipsychotic potential …

E Joseph, S Reddi, V Rinwa, G Balwani… - European Journal of …, 2017 - Elsevier
The present paper discusses the design, characterization and in vivo evaluation of glyceryl
monostearate nanoparticles of Olanzapine, an atypical antipsychotic drug for acute …

Nigella sativa oil entrapped polycaprolactone nanoparticles for leishmaniasis treatment

ES Abamor, OA Tosyali, M Bagirova… - IET …, 2018 - Wiley Online Library
This study is the first to investigate the antileishmanial activities of Nigella sativa oil (NSO)
entrapped poly‐ɛ‐caprolactone (PCL) nanoparticles on Leishmania infantum promastigotes …

[HTML][HTML] Exploring preclinical and clinical effectiveness of nanoformulations in the treatment of atopic dermatitis: Safety aspects and patent reviews

N Akhtar, A Verma, K Pathak - Bulletin of Faculty of Pharmacy, Cairo …, 2017 - Elsevier
Atopic dermatitis (AD) is the most prevalent chronic disease that affects the skin and is
featured by inflammation of the skin. Treatment of AD is entirely focused on to limit the …