[PDF][PDF] Benign breast diseases: classification, diagnosis, and management
M Guray, AA Sahin - The oncologist, 2006 - Wiley Online Library
Learning Objectives After completing this course, the reader will be able to: Discuss the
clinical and histopathologic features of benign conditions of the breast. Identify the risks of …
clinical and histopathologic features of benign conditions of the breast. Identify the risks of …
The roles and regulation of TBX3 in development and disease
TBX3, a member of the ancient and evolutionary conserved T-box transcription factor family,
is a critical developmental regulator of several structures including the heart, mammary …
is a critical developmental regulator of several structures including the heart, mammary …
Genome-wide association analysis identifies three new breast cancer susceptibility loci
Breast cancer is the most common cancer among women. To date, 22 common breast
cancer susceptibility loci have been identified accounting for∼ 8% of the heritability of the …
cancer susceptibility loci have been identified accounting for∼ 8% of the heritability of the …
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis
CL Cai, W Zhou, L Yang, L Bu, Y Qyang, X Zhang, X Li… - 2005 - journals.biologists.com
Mutations in T-box genes are the cause of several congenital diseases and are implicated in
cancer. Tbx20-null mice exhibit severely hypoplastic hearts and express Tbx2, which is …
cancer. Tbx20-null mice exhibit severely hypoplastic hearts and express Tbx2, which is …
Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
The INK4a and ARF genes found at the CDKN2A locus are key effectors of cellular
senescence that is believed to act as a powerful anticancer mechanism. Accordingly …
senescence that is believed to act as a powerful anticancer mechanism. Accordingly …
Tbx3 is a downstream target of the Wnt/β-catenin pathway and a critical mediator of β-catenin survival functions in liver cancer
CA Renard, C Labalette, C Armengol, D Cougot, Y Wei… - Cancer research, 2007 - AACR
Tbx3 encodes a transcriptional repressor that is important for diverse patterning events
during development, and Tbx3 mutation in humans causes the ulnar-mammary syndrome …
during development, and Tbx3 mutation in humans causes the ulnar-mammary syndrome …
The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell–mediated cancer immunotherapy
C Palena, DE Polev, KY Tsang, RI Fernando… - Clinical cancer …, 2007 - AACR
Purpose: Identification of tumor antigens is essential in advancing immune-based
therapeutic interventions in cancer. Particularly attractive targets are those molecules that …
therapeutic interventions in cancer. Particularly attractive targets are those molecules that …
Tbx3 represses E-cadherin expression and enhances melanoma invasiveness
The T-box transcription factors Tbx2 and Tbx3 are overexpressed in many cancers and in
melanoma promote proliferation by actively suppressing senescence. Whether they also …
melanoma promote proliferation by actively suppressing senescence. Whether they also …
The T‐box transcription factor Tbx2: its role in development and possible implication in cancer
Tbx2 is a member of the T‐box family of transcription factors that are crucial in embryonic
development. Recent studies suggest that T‐box factors may also play a role in controlling …
development. Recent studies suggest that T‐box factors may also play a role in controlling …
Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma
TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3
function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary …
function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary …