Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Lipopeptides as tools in catalysis, supramolecular, materials and medicinal chemistry

C Vicente-Garcia, I Colomer - Nature Reviews Chemistry, 2023 - nature.com
Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C
or N terminus of peptides. Their self-assembly—into micelles, vesicles, nanotubes, fibres or …

Lipopeptides: from self-assembly to bioactivity

IW Hamley - Chemical Communications, 2015 - pubs.rsc.org
This Feature Article discusses several classes of lipopeptide with important biomedical
applications as antimicrobial and antifungal agents, in immune therapies and in personal …

Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials

CJC Edwards-Gayle, IW Hamley - Organic & biomolecular chemistry, 2017 - pubs.rsc.org
Molecular self-assembly is a multi-disciplinary field of research, with potential chemical and
biological applications. One of the main driving forces of self-assembly is molecular …

Peptide hormones and lipopeptides: from self‐assembly to therapeutic applications

JA Hutchinson, S Burholt… - Journal of Peptide …, 2017 - Wiley Online Library
This review describes the properties and activities of lipopeptides and peptide hormones
and how the lipidation of peptide hormones could potentially produce therapeutic agents …

Lipopeptides for vaccine development

IW Hamley - Bioconjugate Chemistry, 2021 - ACS Publications
The development of lipopeptides (lipidated peptides) for vaccines is discussed, including
their role as antigens and/or adjuvants. Distinct classes of lipopeptide architectures are …

Advances and opportunities in nanoparticle‐and nanomaterial‐based vaccines against bacterial infections

LCW Lin, S Chattopadhyay, JC Lin… - Advanced healthcare …, 2018 - Wiley Online Library
As the dawn of the postantibiotic era we approach, antibacterial vaccines are becoming
increasingly important for managing bacterial infection and reducing the need for antibiotics …

[HTML][HTML] Small-angle scattering techniques for peptide and peptide hybrid nanostructures and peptide-based biomaterials

IW Hamley, V Castelletto - Advances in Colloid and Interface Science, 2023 - Elsevier
The use of small-angle scattering (SAS) in the study of self-assembly of peptides and
peptide conjugates (lipopeptides, polymer-peptide conjugates and others) is reviewed …

Toll-like receptor agonist conjugation: a chemical perspective

BJ Ignacio, TJ Albin, AP Esser-Kahn… - Bioconjugate …, 2018 - ACS Publications
Toll-like receptors (TLRs) are vital elements of the mammalian immune system that function
by recognizing pathogen-associated molecular patterns (PAMPs), bridging innate and …

Toll‐like receptors: The role in bladder cancer development, progression and immunotherapy

S Ohadian Moghadam… - Scandinavian journal of …, 2019 - Wiley Online Library
Bladder cancer is one of the leading causes of death worldwide. The main immune
mechanisms which lead to bladder cancer development or treatment outcomes have yet to …