Celastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine
Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular …

The identification of new bioactive compounds derived from medicinal plants with significant
therapeutic properties has attracted considerable interest in recent years. Such is the case of …

Abstract Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase that
regulates many cellular processes. Given the central role of PP2A in regulating diverse …

Celastrol, a principal bioactive ingredient of Tripterygium wilfordii Hook F, has gained
extensive exploration due to its unique structure features and multiple promising biological …

Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the
discovery of phytocannabinoids, including the Cannabis major psychoactive compound—Δ9 …

Despite the advancement in the well-equipped and sophisticated laboratories and facilities,
cancer remains to be a major cause of death worldwide. Consequently, further investigation …

Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes
ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM) …

Free radicals with reactive chemical properties can fight tumors without causing drug
resistance. Reactive oxygen species (ROS) has been widely used for cancer treatment, but …

Lariciresinol (LA) is one of the main active ingredients in many traditional medicinal plants
such as Patrinia, and has the role of anti-liver cancer. However, the precise mechanisms are …

Celastrol is a bioactive compound derived from traditional Chinese medicinal herbs of the
Celastraceae family. Celastrol is known to possess anti-inflammatory and anti-oxidant …