The faster-X effect: integrating theory and data

RP Meisel, T Connallon - Trends in genetics, 2013 - cell.com
Population genetics theory predicts that X (or Z) chromosomes could play disproportionate
roles in speciation and evolutionary divergence, and recent genome-wide analyses have …

Estimation of the Spontaneous Mutation Rate per Nucleotide Site in a Drosophila melanogaster Full-Sib Family

PD Keightley, RW Ness, DL Halligan, PR Haddrill - Genetics, 2014 - academic.oup.com
We employed deep genome sequencing of two parents and 12 of their offspring to estimate
the mutation rate per site per generation in a full-sib family of Drosophila melanogaster …

The Relations Between Recombination Rate and Patterns of Molecular Variation and Evolution in Drosophila

B Charlesworth, JL Campos - Annual review of genetics, 2014 - annualreviews.org
Genetic recombination affects levels of variability and the efficacy of selection because
natural selection acting at one site affects evolutionary processes at linked sites. The …

The Relation between Recombination Rate and Patterns of Molecular Evolution and Variation in Drosophila melanogaster

JL Campos, DL Halligan, PR Haddrill… - Molecular biology …, 2014 - academic.oup.com
Genetic recombination associated with sexual reproduction increases the efficiency of
natural selection by reducing the strength of Hill–Robertson interference. Such interference …

Background Selection as Baseline for Nucleotide Variation across the Drosophila Genome

JM Comeron - PLoS Genetics, 2014 - journals.plos.org
The constant removal of deleterious mutations by natural selection causes a reduction in
neutral diversity and efficacy of selection at genetically linked sites (a process called …

Faster‐X evolution: Theory and evidence from Drosophila

B Charlesworth, JL Campos, BC Jackson - Molecular ecology, 2018 - Wiley Online Library
A faster rate of adaptive evolution of X‐linked genes compared with autosomal genes can
be caused by the fixation of recessive or partially recessive advantageous mutations, due to …

A comparison of models to infer the distribution of fitness effects of new mutations

A Kousathanas, PD Keightley - Genetics, 2013 - academic.oup.com
Knowing the distribution of fitness effects (DFE) of new mutations is important for several
topics in evolutionary genetics. Existing computational methods with which to infer the DFE …

Pervasive Strong Selection at the Level of Codon Usage Bias in Drosophila melanogaster

HE Machado, DS Lawrie, DA Petrov - Genetics, 2020 - academic.oup.com
Codon usage bias (CUB), where certain codons are used more frequently than expected by
chance, is a ubiquitous phenomenon and occurs across the tree of life. The dominant …

Population Genomics of Daphnia pulex

M Lynch, R Gutenkunst, M Ackerman, K Spitze, Z Ye… - Genetics, 2017 - academic.oup.com
Using data from 83 isolates from a single population, the population genomics of the
microcrustacean Daphnia pulex are described and compared to current knowledge for the …

The effects on neutral variability of recurrent selective sweeps and background selection

JL Campos, B Charlesworth - Genetics, 2019 - academic.oup.com
Levels of variability and rates of adaptive evolution may be affected by hitchhiking, the effect
of selection on evolution at linked sites. Hitchhiking can be caused either by “selective …