Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer

S Banerjee, M Hatimuria, K Sarkar, J Das… - Chemical Research …, 2023 - ACS Publications
Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

Lipid dysregulation in triple negative breast cancer: Insights from mass spectrometry-based approaches

X Huang, A Ali, DEI Yachioui, SE Le Dévédec… - Progress in Lipid …, 2025 - Elsevier
Triple negative breast cancer (TNBC) has the worst prognosis among breast cancers due to
its aggressive nature and the absence of targeted treatments. Development of novel anti …

Evaluation of two simultaneous metabolomic and proteomic extraction protocols assessed by ultra-high-performance liquid chromatography tandem mass …

RA Zenati, AD Giddey, HM Al-Hroub… - International Journal of …, 2023 - mdpi.com
Untargeted multi-omics analysis of plasma is an emerging tool for the identification of novel
biomarkers for evaluating disease prognosis, and for develo** a better understanding of …

[HTML][HTML] Multi-omics analysis revealed significant metabolic changes in brain cancer cells treated with paclitaxel and/or topotecan

AM Semreen, LO Alsoud, MH Semreen, M Ahmed… - Heliyon, 2024 - cell.com
Glioblastoma (GBM) stands as the most common primary malignant brain tumor. Despite the
best standard therapies, GBM survivors have a brief survival time, about 24 months on …

S100A6 mediated epithelial-mesenchymal transition affects chemosensitivity of colorectal cancer to oxaliplatin

C Zhang, M Zeng, Y Xu, B Huang, P Shi, X Zhu, Y Cao - Gene, 2024 - Elsevier
Purpose To investigate the mechanism by which S100 calcium-binding protein A6 (S100A6)
affects colorectal cancer (CRC) cells to oxaliplatin (L-OHP) chemotherapy, and to explore …

Mass spectrometric analysis of bioactive conditioned media of bacteria isolated from reptilian gut

R Siddiqui, N Akbar, NC Soares, HM Al-Hroub… - Future Science …, 2023 - Taylor & Francis
Aim: To determine whether selected gut bacteria of crocodile exhibit antibacterial properties.
Materials & methods: Two bacteria isolated from Crocodylus porosus gut were used …

[HTML][HTML] Analysis of TLR2 in Primary Endocrine Resistant of Breast Cancer

Y Wang, G Wang, X Wang, J Yang, Y Shen… - Frontiers in Bioscience …, 2024 - imrpress.com
Background: Previous clinical studies have suggested that Toll-like receptor (TLR) 2 had
predictive function for endocrine resistance in HER2-positive breast cancer (BCa) …

Integrated multi‐omics analysis reveals unique signatures of paclitaxel‐loaded poly(lactide‐co‐glycolide) nanoparticles treatment of head and neck cancer cells

M Haider, J Jagal, K Bajbouj, BM Sharaf… - …, 2023 - Wiley Online Library
The use of poly (lactide‐co‐glycolide)(PLGA) nanoparticles (NPs) as carriers for
chemotherapeutic drugs is regarded as an actively targeted nano‐therapy for the specific …

[HTML][HTML] High-Throughput Chromatography for Clinical Proteomics Applications

G Mitulović, JM Vukajlović - Relevant Applications of High …, 2024 - intechopen.com
It is becoming increasingly important to use high-throughput analysis of clinical samples to
monitor the progression or regression of disease or the concentration of therapeutic agents …