Anaphylaxis is a severe, acute, life-threatening multisystem allergic reaction resulting from
the release of a plethora of mediators from mast cells culminating in serious respiratory …

Mast cells are derived from hematopoietic stem cell precursors and are essential to the
genesis and manifestations of the allergic response. Activation of these cells by allergens …

It is currently believed that innate immunity is unable to prevent the spread of SARS-CoV-2
from the upper airways to the alveoli of high-risk groups of patients. SARS-CoV-2 replication …

Platelet-derived extracellular vesicles (PEVs) play important roles in hemostasis and
thrombosis. There are three major types of PEVs described based on their size and …

Anaphylaxis is a systemic hypersensitivity reaction that can be life threatening.
Mechanistically, it results from the immune activation and release of a variety of mediators …

Purpose. Mucopolysaccharidoses (MPS) are group of inherited lysosomal storage diseases
caused by mutations of enzymes involved in catalyzing different glycosaminoglycans …

From the viewpoint of the general pathology, most of the human diseases are associated
with a limited number of pathogenic processes such as inflammation, tumor growth …

Anaphylaxis is a life-threatening allergic reaction. It is triggered by the release of pro-
inflammatory cytokines and mediators from mast cells and basophils in response to …

Advances in next generation sequencing technologies, as well as their expanded
accessibility and clinical use over the past 2 decades, have led to an exponential increase in …

Since the emergency of Covid‐19 in December 2019 in Wuhan, China, WHO declared
Covid‐19 to be a global pandemic crisis on March 11, 2020. 1 The key in facing this …