Sensitive and amplification-free electrochemiluminescence biosensor for HPV-16 detection based on CRISPR/Cas12a and DNA tetrahedron nanostructures
L Yu, Y Peng, M Sheng, Q Wang, J Huang, X Yang - ACS sensors, 2023 - ACS Publications
Rapid and accurate detection of biomarkers was very important for early screening and
treatment of diseases. Herein, a sensitive and amplification-free electrochemiluminescence …
treatment of diseases. Herein, a sensitive and amplification-free electrochemiluminescence …
Ultrasensitive CRISPR/Cas13a-mediated photoelectrochemical biosensors for specific and direct assay of miRNA-21
L Jiang, J Du, H Xu, X Zhuo, J Ai, J Zeng… - Analytical …, 2023 - ACS Publications
Sensitive and specific assay of microRNAs (miRNAs) is beneficial to early disease
screening. Herein, we for the first time proposed clustered regularly interspaced short …
screening. Herein, we for the first time proposed clustered regularly interspaced short …
Recent strategies for electrochemical sensing detection of miRNAs in lung cancer
K Han, H Liu, J Cui, Y Liu, P Pan - Analytical Biochemistry, 2023 - Elsevier
MicroRNAs (miRNAs) associated with lung cancer are diversifying. MiR-21, Let-7, and miR-
141 are common diagnostic targets. Some new lung cancer miRNAs, such as miR-25, miR …
141 are common diagnostic targets. Some new lung cancer miRNAs, such as miR-25, miR …
Non-canonical CRISPR/Cas12a-based technology: A novel horizon for biosensing in nucleic acid detection
X Lei, S Cao, T Liu, Y Wu, S Yu - Talanta, 2024 - Elsevier
Nucleic acids are essential biomarkers in molecular diagnostics. The CRISPR/Cas system
has been widely used for nucleic acid detection. Moreover, canonical CRISPR/Cas12a …
has been widely used for nucleic acid detection. Moreover, canonical CRISPR/Cas12a …
A self-supply crRNA-mediated CRISPR/Cas12a-driven controlled-release homogeneous biosensor for ultrasensitive detection of microRNA
J Dong, S Zhou, Y Liu, L Deng, Z Huang, J Chen… - Chemical Engineering …, 2023 - Elsevier
The abnormal expression of microRNAs (miRNAs) will lead to the occurrence of cancer and
serious genetic related diseases. In this work, a novel self-supply crRNA-mediated …
serious genetic related diseases. In this work, a novel self-supply crRNA-mediated …
CRISPR-Cas12a coupled with universal gold nanoparticle strand-displacement probe for rapid and sensitive visual SARS-CoV-2 detection
S Liu, T **e, X Pei, S Li, Y He, Y Tong, G Liu - Sensors and Actuators B …, 2023 - Elsevier
Point of care (POC) diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) are particularly significant for preventing transmission of coronavirus disease 2019 …
CoV-2) are particularly significant for preventing transmission of coronavirus disease 2019 …
Photoresponsive CHA-Integrated Self-Propelling 3D DNA Walking Amplifier within the Concentration Localization Effect of DNA Molecular Framework Enables Highly …
JW He, X Sun, HW Tang, D Liu, CY Li - Analytical Chemistry, 2024 - ACS Publications
While three-dimensional (3D) DNA walking amplifiers hold considerable promise in the
construction of advanced DNA-based fluorescent biosensors for bioimaging, they encounter …
construction of advanced DNA-based fluorescent biosensors for bioimaging, they encounter …
A photoelectrochemical biosensor based on ZnIn2S4@ AuNPs coupled with circular bipedal DNA walker for signal-on detection of circulating tumor DNA
YB Cui, H Yan, Z Sun, Y Ling, HQ Luo, NB Li - Biosensors and …, 2023 - Elsevier
The circulating tumor DNA (ctDNA) is a crucial cancer marker, its sensitive monitoring is
useful for early diagnose and therapy of tumor-related diseases. Herein, a bipedal DNA …
useful for early diagnose and therapy of tumor-related diseases. Herein, a bipedal DNA …
Exonuclease-catalyzed recycling and annular four-footed DNA walking amplification-assisted “on-off-super on” signal transitions for photoelectrochemical biosensing …
J Wang, J Chen, W Huang, X Li, G Lai - Biosensors and Bioelectronics, 2024 - Elsevier
Photoelectrochemical (PEC) biosensors have exhibited a promising potential for assays of a
large variety of analytes; however, how to realize their low background-based “super on” …
large variety of analytes; however, how to realize their low background-based “super on” …
A label-free electrochemical sensor for the detection of two kinds of targets based on CRISPR/Cas12a system
B Liu, W Lu, Y Huang, X Zhang, X Yuan - Sensors and Actuators B …, 2024 - Elsevier
In recent years, electrochemical sensors for nucleic acid testing based on CRISPR/Cas12a
technology have attracted widespread interest due to their ease of operation and high …
technology have attracted widespread interest due to their ease of operation and high …