Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis
A fundamental metabolic feature of cancerous tissues is high glucose consumption. The rate
of glucose consumption in a cancer cell can be 10–15 times higher than in normal cells …
of glucose consumption in a cancer cell can be 10–15 times higher than in normal cells …
Metal speciation in health and medicine represented by iron and vanadium
DC Crans, KA Woll, K Prusinskas, MD Johnson… - Inorganic …, 2013 - ACS Publications
The influence of metals in biology has become more and more apparent within the past
century. Metal ions perform essential roles as critical scaffolds for structure and as catalysts …
century. Metal ions perform essential roles as critical scaffolds for structure and as catalysts …
A review on coordination properties of Al (III) and Fe (III) toward natural antioxidant molecules: Experimental and theoretical insights
This review focuses on the ability of some natural antioxidant molecules (ie,
hydroxycinnamic acids, coumarin-3-carboxylic acid, quercetin, luteolin and curcumin) to …
hydroxycinnamic acids, coumarin-3-carboxylic acid, quercetin, luteolin and curcumin) to …
Selective speciation improves efficacy and lowers toxicity of platinum anticancer and vanadium antidiabetic drugs
KA Doucette, KN Hassell, DC Crans - Journal of Inorganic Biochemistry, 2016 - Elsevier
Improving efficacy and lowering resistance to metal-based drugs can be addressed by
consideration of the coordination complex speciation and key reactions important to …
consideration of the coordination complex speciation and key reactions important to …
Metal chelation therapy and Parkinson's disease: A critical review on the thermodynamics of complex formation between relevant metal ions and promising or …
M Tosato, V Di Marco - Biomolecules, 2019 - mdpi.com
The present review reports a list of approximately 800 compounds which have been used,
tested or proposed for Parkinson's disease (PD) therapy in the year range 2014–2019 …
tested or proposed for Parkinson's disease (PD) therapy in the year range 2014–2019 …
Differential metal ion sensing by an antipyrine derivative in aqueous and β-cyclodextrin media: selectivity tuning by β-cyclodextrin
GT Selvan, S Poomalai, S Ramasamy… - Analytical …, 2018 - ACS Publications
β-Cyclodextrin (β-CD) is a nontoxic cyclic oligosachcharide that can encapsulate all or part
of organic molecules of appropriate size and specific shape through noncovalent interaction …
of organic molecules of appropriate size and specific shape through noncovalent interaction …
Medicinal chemistry of metal chelating fragments in metalloenzyme active sites: A perspective
Z Jiang, Q You, X Zhang - European Journal of Medicinal Chemistry, 2019 - Elsevier
Numerous metal-containing enzymes (metalloenzymes) have been considered as drug
targets related to diseases such as cancers, diabetes, anemia, AIDS, malaria, bacterial …
targets related to diseases such as cancers, diabetes, anemia, AIDS, malaria, bacterial …
Nanotechnologies and controlled release formulations for the administration of bisphosphonates and their potential in radiation protection
G Landon, G Phan, F Fay, C Bouvier-Capely… - Journal of Drug Delivery …, 2023 - Elsevier
In the event of internal contamination with radionuclides, decorporating treatment is crucial.
It must be initiated as soon as possible to limit tissue retention of radiocontaminants and …
It must be initiated as soon as possible to limit tissue retention of radiocontaminants and …
Aluminum contamination in parenteral products
KM Gura - Current Opinion in Clinical Nutrition & Metabolic Care, 2014 - journals.lww.com
Unlike the rapid response to eliminating aluminum toxicity in the dialysis patient population,
similar successes have not been realized in patients receiving parenteral nutrition solutions …
similar successes have not been realized in patients receiving parenteral nutrition solutions …
Zinc supplementation alters plasma aluminum and selenium status of patients undergoing dialysis: a pilot study
CH Guo, PC Chen, GSW Hsu, CL Wang - Nutrients, 2013 - mdpi.com
End stage renal disease patients undergoing long-term dialysis are at risk for abnormal
concentrations of certain essential and non-essential trace metals and high oxidative stress …
concentrations of certain essential and non-essential trace metals and high oxidative stress …