There is little information on inbreeding during the critical early years of human existence.
However, given the small founding group sizes and restricted mate choices it seems …

Marriage between close biological relatives is generally regarded with suspicion and
distaste within Western society, reflecting historical and religious prejudice. By comparison …

Abstract The Greater Middle East (GME) has been a central hub of human migration and
population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf …

The human genome is characterised by many runs of homozygous genotypes, where
identical haplotypes were inherited from each parent. The length of each run is determined …

Intellectual disability (ID), also referred to as mental retardation (MR), is frequently the result
of genetic mutation. Where ID is present together with additional clinical symptoms or …

Consanguineous marriage is a major feature of family systems in south-west Asia. The aim
of the present study was to determine the current prevalence and patterns of consanguinity …

Approximately 1% of the global population is affected by intellectual disability (ID), and the
majority receive no molecular diagnosis. Previous studies have indicated high levels of …

Background Pakistan has been showing consistently the highest prevalence of
consanguinity. The popularity of consanguineous marriages is not declining in the country …

Background Low birthweight is a widely used indicator of newborn health. This study
investigates the association of birthweight< 2.5 kg (LBW) with a wide range of factors related …

Introduction This study aimed to assess the prevalence, sociodemographic factors,
reproductive consequences, and heritable disease burdens associated with …