The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms
We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …
Toll-like receptor signaling and its role in cell-mediated immunity
Innate immunity is the first defense system against invading pathogens. Toll-like receptors
(TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition …
(TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition …
The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee
Since the publication of the Revised European-American Classification of Lymphoid
Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have …
Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have …
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
SH Swerdlow, E Campo, SA Pileri… - Blood, The Journal …, 2016 - ashpublications.org
A revision of the nearly 8-year-old World Health Organization classification of the lymphoid
neoplasms and the accompanying monograph is being published. It reflects a consensus …
neoplasms and the accompanying monograph is being published. It reflects a consensus …
A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study
Bruton tyrosine kinase (BTK) inhibition is an effective treatment approach for patients with
Waldenström macroglobulinemia (WM). The phase 3 ASPEN study compared the efficacy …
Waldenström macroglobulinemia (WM). The phase 3 ASPEN study compared the efficacy …
NF‐κB signaling in inflammation and cancer
T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …
in 1986, extraordinary efforts have been made to understand the function and regulating …
Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting
U Jäger, W Barcellini, CM Broome, MA Gertz, A Hill… - Blood reviews, 2020 - Elsevier
Autoimmune hemolytic anemias (AIHAs) are rare and heterogeneous disorders
characterized by the destruction of red blood cells through warm or cold antibodies. There is …
characterized by the destruction of red blood cells through warm or cold antibodies. There is …
Role of Bruton's tyrosine kinase in B cells and malignancies
S Pal Singh, F Dammeijer, RW Hendriks - Molecular cancer, 2018 - Springer
Bruton's tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic
signaling that is critical for proliferation and survival of leukemic cells in many B cell …
signaling that is critical for proliferation and survival of leukemic cells in many B cell …
Ibrutinib in previously treated Waldenström's macroglobulinemia
SP Treon, CK Tripsas, K Meid, D Warren… - … England Journal of …, 2015 - Mass Medical Soc
Background MYD88 L265P and CXCR4WHIM mutations are highly prevalent in
Waldenström's macroglobulinemia. MYD88L265P triggers tumor-cell growth through …
Waldenström's macroglobulinemia. MYD88L265P triggers tumor-cell growth through …
Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis
SN Stacey, F Zink, GH Halldorsson, L Stefansdottir… - Nature Genetics, 2023 - nature.com
Clonal hematopoiesis (CH) arises when a substantial proportion of mature blood cells is
derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of …
derived from a single hematopoietic stem cell lineage. Using whole-genome sequencing of …