Cognitive deficits in psychotic disorders: a lifespan perspective

JM Sheffield, NR Karcher, DM Barch - Neuropsychology review, 2018 - Springer
Individuals with disorders that include psychotic symptoms (ie psychotic disorders)
experience broad cognitive impairments in the chronic state, indicating a dimension of …

Bipolar disorder

I Grande, M Berk, B Birmaher, E Vieta - The Lancet, 2016 - thelancet.com
Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state
and energy. It affects more than 1% of the world's population irrespective of nationality …

The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management

RS McIntyre, M Alda, RJ Baldessarini, M Bauer… - World …, 2022 - Wiley Online Library
Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

Early intervention in bipolar disorder

E Vieta, E Salagre, I Grande… - American Journal of …, 2018 - Am Psychiatric Assoc
Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and
usually has its onset during youth. Its chronic course is associated with high rates of …

Biological hypotheses and biomarkers of bipolar disorder

E Sigitova, Z Fišar, J Hroudová… - Psychiatry and …, 2017 - Wiley Online Library
The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

Can bipolar disorder be viewed as a multi-system inflammatory disease?

M Leboyer, I Soreca, J Scott, M Frye, C Henry… - Journal of affective …, 2012 - Elsevier
BACKGROUND: Patients with bipolar disorder are known to be at high risk of premature
death. Comorbid cardio-vascular diseases are a leading cause of excess mortality, well …

Staging in bipolar disorder: from theoretical framework to clinical utility

M Berk, R Post, A Ratheesh, E Gliddon… - World …, 2017 - Wiley Online Library
Illness staging is widely utilized in several medical disciplines to help predict course or
prognosis, and optimize treatment. Staging models in psychiatry in general, and bipolar …

Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder

AC Andreazza, L Shao, JF Wang… - Archives of general …, 2010 - jamanetwork.com
Context Accumulating evidence suggests that mitochondrial dysfunction and oxidative stress
contribute to the pathogenesis of bipolar disorder and schizophrenia. It remains unclear …

Clinical staging in psychiatry: a cross-cutting model of diagnosis with heuristic and practical value

J Scott, M Leboyer, I Hickie, M Berk… - The British journal of …, 2013 - cambridge.org
Staging models are used routinely in general medicine for potentially serious or chronic
physical disorders such as diabetes, arthritis and cancers, describing the links between …

Areas of controversy in neuroprogression in bipolar disorder

IC Passos, B Mwangi, E Vieta, M Berk… - Acta Psychiatrica …, 2016 - Wiley Online Library
Objective We aimed to review clinical features and biological underpinnings related to
neuroprogression in bipolar disorder (BD). Also, we discussed areas of controversy and …