[HTML][HTML] Virus exposure and neurodegenerative disease risk across national biobanks

KS Levine, HL Leonard, C Blauwendraat, H Iwaki… - Neuron, 2023 - cell.com
With recent findings connecting the Epstein-Barr virus to an increased risk of multiple
sclerosis and growing concerns regarding the neurological impact of the coronavirus …

Mendelian randomization as a tool for causal inference in human nutrition and metabolism

SC Larsson - Current opinion in lipidology, 2021 - journals.lww.com
Mendelian randomization can be used as a tool to improve causal inference in
observational studies assessing the role of nutritional factors and metabolites in health and …

Bidirectional two-sample Mendelian randomization analysis identifies causal associations between relative carbohydrate intake and depression

S Yao, M Zhang, SS Dong, JH Wang, K Zhang… - Nature human …, 2022 - nature.com
Growing evidence suggests that relative carbohydrate intake affects depression; however,
the association between carbohydrates and depression remains controversial. To test this …

Dietary strategies with anti-aging potential: Dietary patterns and supplements

H Duan, J Pan, M Guo, J Li, L Yu, L Fan - Food Research International, 2022 - Elsevier
Dietary intervention is a safe, broad-spectrum, and low-cost preventive strategy for slow
aging. The Okinawan, Mediterranean, and Dietary approaches to stop hypertension (DASH) …

Gut microbiome variation modulates the effects of dietary fiber on host metabolism

SM Murga-Garrido, Q Hong, TWL Cross, ER Hutchison… - Microbiome, 2021 - Springer
Background There is general consensus that consumption of dietary fermentable fiber
improves cardiometabolic health, in part by promoting mutualistic microbes and by …

Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations

JB Cole, JC Florez, JN Hirschhorn - Nature communications, 2020 - nature.com
Unhealthful dietary habits are leading risk factors for life-altering diseases and mortality.
Large-scale biobanks now enable genetic analysis of traits with modest heritability, such as …

Causal relationship between obesity, lifestyle factors and risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study

YB Wang, L Yang, YQ Deng, SY Yan, LS Luo… - Journal of translational …, 2022 - Springer
Background Obesity (waist circumference, body mass index (BMI)) and lifestyle factors
(dietary habits, smoking, alcohol drinking, Sedentary behavior) have been associated with …

Socioeconomic status, individual behaviors and risk for mental disorders: a Mendelian randomization study

J Cai, Z Wei, M Chen, L He, H Wang, M Li… - European …, 2022 - cambridge.org
Background There is increasing attention on the association of socioeconomic status and
individual behaviors (SES/IB) with mental health. However, the impacts of SES/IB on mental …

[HTML][HTML] Fibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate …

TDV Le, P Fathi, AB Watters, BJ Ellis, GLK Besing… - Molecular …, 2023 - Elsevier
Objective Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1RA) and fibroblast
growth factor-21 (FGF21) confer similar metabolic benefits. GLP-1RA induce FGF21, leading …

Dietary factors and endometrial cancer risk: a mendelian randomization study

X Wang, DM Glubb, TA O'Mara - Nutrients, 2023 - mdpi.com
Given the strong association between obesity and endometrial cancer risk, dietary factors
may play an important role in the development of this cancer. However, observational …