More than just a barrier: using physical models to couple membrane shape to cell function

F Frey, T Idema - Soft matter, 2021 - pubs.rsc.org
The correct execution of many cellular processes, such as division and motility, requires the
cell to adopt a specific shape. Physically, these shapes are determined by the interplay of …

Interactions between model inclusions on closed lipid bilayer membranes

T Idema, DJ Kraft - Current Opinion in Colloid & Interface Science, 2019 - Elsevier
Protein inclusions in the membranes of living cells interact via the deformations they impose
on that membrane. Such membrane-mediated interactions lead to sorting and self-assembly …

Curvature variation controls particle aggregation on fluid vesicles

A Vahid, A Šarić, T Idema - Soft Matter, 2017 - pubs.rsc.org
Cellular membranes exhibit a large variety of shapes, strongly coupled to their function.
Many biological processes involve dynamic resha** of membranes, usually mediated by …

[HTML][HTML] Nonadditivity in interactions between three membrane-wrapped colloidal spheres

A Azadbakht, B Meadowcroft, J Májek, A Šarić… - Biophysical …, 2024 - cell.com
Many cell functions require a concerted effort from multiple membrane proteins, for example,
for signaling, cell division, and endocytosis. One contribution to their successful self …

Monolayerwise application of linear elasticity theory well describes strongly deformed lipid membranes and the effect of solvent

TR Galimzyanov, PV Bashkirov, PS Blank… - Soft Matter, 2020 - pubs.rsc.org
The theory of elasticity of lipid membranes is used widely to describe processes of cell
membrane remodeling. Classically, the functional of a membrane's elastic energy is derived …

Membrane-mediated interactions between protein inclusions

J Gao, R Hou, L Li, J Hu - Frontiers in molecular biosciences, 2021 - frontiersin.org
Integral or peripheral membrane proteins, or protein oligomers often get close to each other
on cell membranes and carry out biological tasks in a collective manner. In addition to …

Conformations and membrane-driven self-organization of rodlike fd virus particles on freestanding lipid membranes

AB Petrova, C Herold, EP Petrov - Soft Matter, 2017 - pubs.rsc.org
Membrane-mediated interactions and aggregation of colloidal particles adsorbed to
responsive elastic membranes are challenging problems relevant for understanding the …

Membrane protein clustering from tension and multibody interactions

JB Fournier - Europhysics Letters, 2024 - iopscience.iop.org
The point-curvature model for membrane protein inclusions is shown to capture multibody
interactions very well. Using this model, we find that the interplay between membrane …

Multibody interactions between protein inclusions in the pointlike curvature model for tense and tensionless membranes

JB Fournier - The European Physical Journal E, 2024 - Springer
The pointlike curvature constraint (PCC) model and the disk detachment angle (DDA) model
for the deformation-mediated interaction of conical integral protein inclusions in …

Protein recruitment through indirect mechanochemical interactions

A Goychuk, E Frey - Physical Review Letters, 2019 - APS
Some of the key proteins essential for important cellular processes are capable of recruiting
other proteins from the cytosol to phospholipid membranes. The physical basis for this …