Members of the transforming growth factor-β (TGF-β) superfamily have wide-ranging
influences on many tissue and organ systems including the ovary. Two recently discovered …

The ovary is a complex endocrine gland responsible for production of sex steroids and is the
source of fertilizable ova for reproduction. It also produces various growth factors …

Survival and inhibitory factors regulate steroidogenesis and determine the fate of develo**
follicles. The objective of this study was to determine the role of transforming growth factor …

We have investigated the biological characteristics of an immortalized granulosa cell line
(COV434), which may be used to study follicular and oocyte maturation in vitro. Granulosa …

Heat stress affects granulosa cells and the ovarian follicular microenvironment, ultimately
resulting in poor oocyte developmental competence. This study aims to investigate the …

The yak, a unique species of cattle found exclusively on the western plateau of China, is a
valuable source of livelihood for local residents. However, their low fecundity restricts the …

Ovarian granulosa cells (GC) are the major source of estradiol synthesis. Induced by the
preovulatory luteinizing hormone (LH) surge, cells of the theca and, in particular, of the …

Survival and inhibitory factors regulate steroidogenesis and determine the fate of develo**
follicles. The objective of this study was to determine the role of transforming growth factor …

Anti-Müllerian hormone (AMH) produced by granulosa cells has previously been proposed
to play a role in regulating granulosa cell differentiation and follicle selection. Although AMH …

Oocytes are powerful local modulators of follicular cell functions and many of the activities of
oocytes are attributed to members of the transforming growth factor-β (TGF-β) superfamily …