Accurate detection of identity-by-descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick, I Olalde… - Nature Genetics, 2024 - nature.com
Long DNA segments shared between two individuals, known as identity-by-descent (IBD),
reveal recent genealogical connections. Here we introduce ancIBD, a method for identifying …

The genetic legacy of African Americans from Catoctin furnace

É Harney, S Micheletti, KS Bruwelheide, WA Freyman… - Science, 2023 - science.org
Few African Americans have been able to trace family lineages back to ancestors who died
before the 1870 United States Census, the first in which all Black people were listed by …

From Biobanking to Personalized Medicine: the journey of the Estonian Biobank

L Milani, M Alver, S Laur, S Reisberg, T Haller… - medRxiv, 2024 - medrxiv.org
Large biobanks have set a new standard for research and innovation in human genomics
and implementation of personalised medicine. The Estonian Biobank was founded a quarter …

Genetic history of Cambridgeshire before and after the Black Death

R Hui, CL Scheib, E D'Atanasio, SA Inskip… - Science …, 2024 - science.org
The extent of the devastation of the Black Death pandemic (1346–1353) on European
populations is known from documentary sources and its bacterial source illuminated by …

[HTML][HTML] ancIBD-Screening for identity by descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick… - BioRxiv, 2023 - ncbi.nlm.nih.gov
Long DNA sequences shared between two individuals, known as Identical by descent (IBD)
segments, are a powerful signal for identifying close and distant biological relatives because …

Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders

S Sasso, L Saag, R Spros, O Beneker… - Proceedings of the …, 2024 - pnas.org
The Merovingian period (5th to 8th cc AD) was a time of demographic, socioeconomic,
cultural, and political realignment in Western Europe. Here, we report the whole-genome …

Use of Estonian Biobank data and participant recall to improve Wilson's disease management

M Nurm, A Reigo, T Annilo, T Toomsoo… - European Journal of …, 2024 - nature.com
Population-based biobanks enable genomic screening to support initiatives that prevent
disease onset or slow its progression and to estimate the prevalence of genetic diseases in …

Y chromosome sequencing data suggest dual paths of haplogroup N1a1 into Finland

A Preussner, J Leinonen, J Riikonen… - European Journal of …, 2024 - nature.com
The paternally inherited Y chromosome is highly informative of genetic ancestry, therefore
making it useful in studies of population history. In Finland, two Y-chromosomal haplogroups …

Medieval social landscape through the genetic history of Cambridgeshire before and after the Black Death

R Hui, CL Scheib, E D'Atanasio, SA Inskip, C Cessford… - BioRxiv, 2023 - biorxiv.org
The extent of the devastation of the Black Death pandemic (1346-53) on European
populations is known from documentary sources and its bacterial source illuminated by …

The genetic echo of the Tarim mummies in modern Central Asians

SS Dai, X Sulaiman, J Isakova, WF Xu… - Molecular Biology …, 2022 - academic.oup.com
Abstract The diversity of Central Asians has been shaped by multiple migrations and cultural
diffusion. Although ancient DNA studies have revealed the demographic changes of the …