Human organoids in basic research and clinical applications
Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
either human pluripotent stem cells (hPSCs) or adult stem cells (AdSCs) derived from …
Human organoid models to study SARS-CoV-2 infection
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …
[HTML][HTML] METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection
N Li, H Hui, B Bray, GM Gonzalez, M Zeller… - Cell reports, 2021 - cell.com
It is urgent and important to understand the relationship of the widespread severe acute
respiratory syndrome coronavirus clade 2 (SARS-CoV-2) with host immune response and …
respiratory syndrome coronavirus clade 2 (SARS-CoV-2) with host immune response and …
Discovery and mechanism of SARS-CoV-2 main protease inhibitors
S Huff, IR Kummetha, SK Tiwari… - Journal of medicinal …, 2021 - ACS Publications
The emergence of a new coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), presents an urgent public health crisis. Without available targeted therapies …
(SARS-CoV-2), presents an urgent public health crisis. Without available targeted therapies …
Mechanisms of antiviral immune evasion of SARS-CoV-2
DK Beyer, A Forero - Journal of molecular biology, 2022 - Elsevier
Abstract Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is characterized by a delayed interferon (IFN) response …
coronavirus 2 (SARS-CoV-2) and is characterized by a delayed interferon (IFN) response …
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative
agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by …
agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by …
SARS-CoV-2 promotes microglial synapse elimination in human brain organoids
Neuropsychiatric manifestations are common in both the acute and post-acute phase of
SARS-CoV-2 infection, but the mechanisms of these effects are unknown. In a newly …
SARS-CoV-2 infection, but the mechanisms of these effects are unknown. In a newly …
Organoids: The current status and biomedical applications
S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and therapeutic interventions
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused large-scale
economic and social losses and worldwide deaths. Although most COVID-19 patients have …
economic and social losses and worldwide deaths. Although most COVID-19 patients have …
[HTML][HTML] Complement activation in COVID-19 and targeted therapeutic options: a sco** review
Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …