Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Engineered hydrogels for mechanobiology

U Blache, EM Ford, B Ha, L Rijns… - Nature Reviews …, 2022 - nature.com
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

Directed cell migration towards softer environments

A Isomursu, KY Park, J Hou, B Cheng, M Mathieu… - Nature materials, 2022 - nature.com
How cells sense tissue stiffness to guide cell migration is a fundamental question in
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

The living interface between synthetic biology and biomaterial design

AP Liu, EA Appel, PD Ashby, BM Baker, E Franco… - Nature materials, 2022 - nature.com
Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Toward stimuli‐responsive dynamic thermosets through continuous development and improvements in covalent adaptable networks (CANs)

M Podgórski, BD Fairbanks, BE Kirkpatrick… - Advanced …, 2020 - Wiley Online Library
Covalent adaptable networks (CANs), unlike typical thermosets or other covalently
crosslinked networks, possess a unique, often dormant ability to activate one or more forms …

Design and applications of photoresponsive hydrogels

L Li, JM Scheiger, PA Levkin - Advanced Materials, 2019 - Wiley Online Library
Hydrogels are the most relevant biochemical scaffold due to their tunable properties,
inherent biocompatibility, and similarity with tissue and cell environments. Over the past …

Stimuli‐responsive hydrogels: fabrication and biomedical applications

Z Li, Y Zhou, T Li, J Zhang, H Tian - View, 2022 - Wiley Online Library
Due to their similarity to some bio‐architectures, for example, extracellular matrix, hydrogels
are considered as bio‐inspired networks with bio‐mimetic and bio‐functional properties …