Rethinking the Role of the Nervous System: Lessons From the Hydra Holobiont
Here we evaluate our current understanding of the function of the nervous system in Hydra,
a non‐bilaterian animal which is among the first metazoans that contain neurons. We …
a non‐bilaterian animal which is among the first metazoans that contain neurons. We …
Microbiota–host interactions shape ageing dynamics
Occupying the interface between host and environment, host-associated microbes play
fundamental roles in nutrient absorption, essential metabolite synthesis, development of the …
fundamental roles in nutrient absorption, essential metabolite synthesis, development of the …
Natural genetic variation drives microbiome selection in the Caenorhabditis elegans gut
Host genetic landscapes can shape microbiome assembly in the animal gut by contributing
to the establishment of distinct physiological environments. However, the genetic …
to the establishment of distinct physiological environments. However, the genetic …
Novel technologies uncover novel 'anti'-microbial peptides in Hydra sha** the species-specific microbiome
The freshwater polyp Hydra uses an elaborate innate immune machinery to maintain its
specific microbiome. Major components of this toolkit are conserved Toll-like receptor (TLR) …
specific microbiome. Major components of this toolkit are conserved Toll-like receptor (TLR) …
Novel ADNP syndrome mice reveal dramatic sex-specific peripheral gene expression with brain synaptic and tau pathologies
G Karmon, S Sragovich, G Hacohen-Kleiman… - Biological …, 2022 - Elsevier
Background ADNP is essential for embryonic development. As such, de novo ADNP
mutations lead to an intractable autism/intellectual disability syndrome requiring …
mutations lead to an intractable autism/intellectual disability syndrome requiring …
Dynamic interactions within the host-associated microbiota cause tumor formation in the basal metazoan Hydra
The extent to which disturbances in the resident microbiota can compromise an animal's
health is poorly understood. Hydra is one of the evolutionary oldest animals with naturally …
health is poorly understood. Hydra is one of the evolutionary oldest animals with naturally …
Transgenesis in Hydra to characterize gene function and visualize cell behavior
The freshwater polyp Hydra is a cnidarian used as a model organism in a number of fields,
including the study of the origin and evolution of developmental mechanisms, aging …
including the study of the origin and evolution of developmental mechanisms, aging …
The microbiome mediates environmental effects on aging
Humans' indigenous microbes strongly influence organ functions in an age‐and diet‐
dependent manner, adding an important dimension to aging biology that remains poorly …
dependent manner, adding an important dimension to aging biology that remains poorly …
Symbiotic Algae of Hydra viridissima Play a Key Role in Maintaining Homeostatic Bacterial Colonization
The freshwater polyp Hydra viridissima (H. viridissima) harbors endosymbiotic Chlorella
algae in addition to a species-specific microbiome. The molecular basis of the symbiosis …
algae in addition to a species-specific microbiome. The molecular basis of the symbiosis …
Coral–microbe interactions: their importance to reef function and survival
C Tran - Emerging Topics in Life Sciences, 2022 - portlandpress.com
Many different microorganisms associate with the coral host in a single entity known as the
holobiont, and their interactions with the host contribute to coral health, thereby making them …
holobiont, and their interactions with the host contribute to coral health, thereby making them …