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Advances and utility of the human plasma proteome
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
[HTML][HTML] COVIDomics: The proteomic and metabolomic signatures of COVID-19
Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …
Evidence of structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients
T Thomas, D Stefanoni, M Dzieciatkowska… - Journal of proteome …, 2020 - ACS Publications
The SARS-CoV-2 beta coronavirus is the etiological driver of COVID-19 disease, which is
primarily characterized by shortness of breath, persistent dry cough, and fever. Because they …
primarily characterized by shortness of breath, persistent dry cough, and fever. Because they …
Headache: A striking prodromal and persistent symptom, predictive of COVID-19 clinical evolution
Objective To define headache characteristics and evolution in relation to COVID-19 and its
inflammatory response. Methods This is a prospective study, comparing clinical data and …
inflammatory response. Methods This is a prospective study, comparing clinical data and …
A time-resolved proteomic and prognostic map of COVID-19
COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …
to severe organ damage and death. We characterized the time-dependent progression of …
Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers
FX Danlos, C Grajeda-Iglesias, S Durand… - Cell Death & …, 2021 - nature.com
The circulating metabolome provides a snapshot of the physiological state of the organism
responding to pathogenic challenges. Here we report alterations in the plasma metabolome …
responding to pathogenic challenges. Here we report alterations in the plasma metabolome …
Circulating exosomes are strongly involved in SARS-CoV-2 infection
Knowledge of the host response to the novel coronavirus SARS-CoV-2 remains limited,
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …
Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by highly heterogeneous manifestations ranging from asymptomatic cases to death for still …
by highly heterogeneous manifestations ranging from asymptomatic cases to death for still …
Specialized interferon action in COVID-19
The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both
protective and harmful effects being documented. We report here a multiomics investigation …
protective and harmful effects being documented. We report here a multiomics investigation …
High‐resolution serum proteome trajectories in COVID‐19 reveal patient‐specific seroconversion
A deeper understanding of COVID‐19 on human molecular pathophysiology is urgently
needed as a foundation for the discovery of new biomarkers and therapeutic targets. Here …
needed as a foundation for the discovery of new biomarkers and therapeutic targets. Here …